Long name: |
MHC class I Primary Polyclonal Antibody |
Also known as: |
MHC class I PAb |
Category: |
Primary Antibodies |
Conjugation: |
Unconjugated |
Target Antigen: |
MHC class I |
Specificity: |
This is a highly specific antibody against MHC class I |
Modification(s): |
None |
Modification site(s): |
Unmodified antibody |
Clonality: |
Polyclonal antibody |
Clone number: |
Polyclonal antibody |
Concentration: |
1ug per 1ul |
Subcellular location: |
Extracellular |
Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HLA-A |
Gene ID number: |
93649 |
Tested Applications: |
IF(IHC-P), IHC-P, WB |
Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
Cross reactivity: |
Human |
Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
Background of the target antigen: |
Fibroblasts or neurons however only show a low level of antigen, MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11, The antigen is expressed by all somatic cells at varying levels, which are usually cytotoxic T cells, 5 kDa), MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen |
Purification method: |
This antibody was purified via Protein A |
Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
Synonym names: |
A 28, A 9, Aw 24, Aw 68, CLASS I HISTOCOMPATIBILITY ANTIGEN, H2 K1, H2K, HLA A, HLA class I histocompatibility antigen A 1 alpha chain, HLA class I histocompatibility antigen A 11 alpha chain, HLA class I histocompatibility antigen A 2 alpha chain, HLA class I histocompatibility antigen A 24 alpha chain, HLA class I histocompatibility antigen A 3 alpha chain, HLA class I histocompatibility antigen A 30 alpha chain, HLA class I histocompatibility antigen A 32 alpha chain, HLA class I histocompatibility antigen A 68 alpha chain, HLAA, MHC 1, MHC class I heavy chain H2 K, MHC1, Major histocompatibility complex class I A, MHC-1 |
Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
Gene target: |
MHC class I |
Short name: |
MHC class I Antibody |
Technique: |
antibodies against human proteins, antibodies for, Antibody |
Alternative name: |
Major histocompabitility complex class I (Antibody to) |
Alternative technique: |
antibodies |
Identity: |
7092 |
Gene: |
MICC |
More about : MICC |
Long gene name: |
MHC class I polypeptide-related sequence C (pseudogene) |
Synonyms gene name: |
MHC class I polypeptide-related sequence C |
Synonyms: |
PERB11, 3 |
Locus: |
6p22, 1 |
Discovery year: |
1994-09-07 |
Entrez gene record: |
100129192 |
Pubmed identfication: |
8022771 |
RefSeq identity: |
NG_027534 |
Havana BLAST/BLAT: |
OTTHUMG00000031078 |