| Long name: |
CARD4 Primary Polyclonal Antibody |
| Also known as: |
CARD4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CARD4 |
| Specificity: |
This is a highly specific antibody against CARD4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
64-105/953 |
| Subcellular location: |
Helical |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARD4 |
| Gene ID number: |
10392 |
| Swiss Prot: |
Q9Y239 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS), Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens, Induces NF-kappa-B activity via RIPK2 and IKK-gamma, Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB, Recruits NLRP10 to the cell membrane following bacterial infection, Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathway activation upon S, Enhances caspase-9-mediated apoptosis, flexneri cell invasion |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CLR7, Caspase recruitment domain-containing protein 4, NLRC1, NOD1, Nucleotide-binding oligomerization domain-containing protein 1, 1, CARD4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CARD4 |
| Short name: |
CARD4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CARD4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16390 |
| Gene: |
NOD1 |
More about : NOD1 |
| Long gene name: |
nucleotide binding oligomerization domain containing 1 |
| Synonyms gene: |
CARD4 |
| Synonyms gene name: |
caspase recruitment domain family, member 4 |
| Synonyms: |
NLRC1 CLR7, 1 |
| Synonyms name: |
CARD domain containing 1 , leucine rich repeat and CARD domain containing 1 NLR family, nucleotide-binding oligomerization domain |
| Locus: |
7p14, 3 |
| Discovery year: |
2001-12-11 |
| GenBank acession: |
AF126484 |
| Entrez gene record: |
10392 |
| Pubmed identfication: |
10224040 10329646 |
| Classification: |
Caspase recruitment domain containing NLR family |
| Havana BLAST/BLAT: |
OTTHUMG00000023923 |