| Long name: |
ALEXA FLUOR 488 Conjugated, FTO Polyclonal Antibody |
| Also known as: |
Anti-FTO PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FTO |
| Specificity: |
This is a highly specific antibody against FTO |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
180-230/505 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fat mass and obesity-associated protein |
| Gene ID Number: |
79068 |
| Swiss Prot: |
Q9C0B1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Contributes to the regulation of body size and body fat accumulation, Contributes to the regulation of the global metabolic rate, Has highest activity towards single-stranded RNA containing 3-methyluracil, Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine, Has no activity towards 1-methylguanine, Has no detectable activity towards double-stranded DNA, Requires molecular oxygen, Specifically demethylates N(6)-methyladenosine (m6A) RNA, alpha-ketoglutarate and iron, energy expenditure and energy homeostasis, followed by single-stranded DNA containing 3-methylthymine, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes, Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
KIAA1752 MGC5149 ALKBH9 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FTO Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
FTO |
| Short name: |
FTO Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, fat mass and obesity associated (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-N1-methyladenine dioxygenase activity, FTO and IDBG-31147 and ENSG00000140718 and 79068, FTO and IDBG-631892 and ENSBTAG00000012501 and 618622, Fto and IDBG-179938 and ENSMUSG00000055932 and 26383, nuclei, this GO :0001659 and temperature homeostasis and biological process this GO :0005634 and nucleus and cellular component this GO :0006307 and DNA dealkylation involved in DNA repair and biological process this GO :0008198 and ferrous iron binding and molecular function this GO :0010883 and regulation of lipid storage and biological process this GO :0016607 and nuclear speck and cellular component this GO :0035515 and oxidative RNA demethylase activity and molecular function this GO :0035516 and oxidative DNA demethylase activity and molecular function this GO :0035552 and oxidative single-stranded DNA demethylation and biological process this GO :0035553 and oxidative single-stranded RNA demethylation and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0042245 and RNA repair and biological process this GO :0043734 and DNA-N1-methyladenine dioxygenase activity and molecular function this GO :0044065 and regulation of respiratory system process and biological process this GO :0060612 and adipose tissue development and biological process this GO :0070350 and regulation of white fat cell proliferation and biological process this GO :0070989 and oxidative demethylation and biological process this GO :0080111 and DNA demethylation and biological process, this GO :0008198 : ferrous iron binding, this GO :0008198 : ferrous iron binding and also this GO :0035515 : oxidative RNA demethylase activity and also this GO :0035516 : oxidative DNA demethylase activity and also this GO :0043734 : DNA-N1-methyladenine dioxygenase activity, this GO :0035515 : oxidative RNA demethylase activity, this GO :0035516 : oxidative DNA demethylase activity, this GO :0043734 : DNA-N1-methyladenine dioxygenase activity, fat mass and obesity associated |
| Identity: |
24678 |
| Gene: |
FTO |
More about : FTO |
| Long gene name: |
FTO, alpha-ketoglutarate dependent dioxygenase |
| Synonyms gene name: |
fat mass and obesity associated |
| Synonyms name: |
alkB homolog 9 alpha-ketoglutarate-dependent dioxygenase |
| Locus: |
16q12, 2 |
| Discovery year: |
2007-04-12 |
| GenBank acession: |
BC003583 |
| Entrez gene record: |
79068 |
| Pubmed identfication: |
17434869 17991826 22002720 |
| RefSeq identity: |
NM_001080432 |
| Classification: |
Alkylation repair homologs |
| Havana BLAST/BLAT: |
OTTHUMG00000158780 |