| Long name: |
RCAN2 Primary Polyclonal Antibody |
| Also known as: |
RCAN2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RCAN2 |
| Specificity: |
This is a highly specific antibody against RCAN2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RCAN2 |
| Gene ID number: |
10231 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Calcipressin-2, Calcipressin-3, Calcipressin-3 interacts with cardiac troponin I, Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail, RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells, is a 241 amino acid protein that potentially is involved in central nervous system development, suggesting that it may play a role in cardiac contraction events, which results in either inhibition or activation of calcineurin activity, Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CSP2, Calcipressin-2, Down syndrome candidate region 1-like 1, Down syndrome critical region gene 1 like 1 protein, MCIP2, Myocyte enriched calcineurin interacting protein 2, Myocyte-enriched calcineurin-interacting protein 2, RCAN2, RCAN2_HUMAN, RCN2, Regulator of calcineurin 2, Thyroid hormone responsive protein ZAKI4, Thyroid hormone-responsive protein ZAKI-4, ZAKI4, Calcipressin 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RCAN2 |
| Short name: |
RCAN2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RCAN2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3041 |
| Gene: |
RCAN2 |
More about : RCAN2 |
| Long gene name: |
regulator of calcineurin 2 |
| Synonyms gene: |
DSCR1L1 |
| Synonyms gene name: |
Down syndrome critical region gene 1-like 1 |
| Synonyms: |
ZAKI-4 |
| Locus: |
6p12, 3 |
| Discovery year: |
1999-08-20 |
| GenBank acession: |
D83407 |
| Entrez gene record: |
10231 |
| Pubmed identfication: |
8662924 |
| Havana BLAST/BLAT: |
OTTHUMG00000014782 |