| Long name: |
O-GlcNAc transferase Primary Polyclonal Antibody |
| Also known as: |
O-GlcNAc transferase PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
O-GlcNAc transferase |
| Specificity: |
This is a highly specific antibody against O-GlcNAc transferase |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human O-GlcNAc transferase |
| Gene ID number: |
8473 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Both polypeptides are related, HeLa cells expressing O-GlcNAc transferase do not survive well during prolonged incubations, Immunofluorescence of human cells expressing rat O-GlcNAc transferase indicated that it is present in both the nucleus and cytosol, It exists as a heterotrimeric complex with two subunits of the same molecular mass and one shorter subunit, Mediates the O-glycosylation of MLL5 and HCFC1, O-GlcNAc transferase has been purified from rat liver, O-GlcNAc transferase is expressed as multiple transcripts that are present in different amounts in various human tissues, Promotes proteolytic maturation of HCFC1, Since both phosphorylation and glycosylation compete for similar serine or threonine residues, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects, suggesting that this protein may be toxic to the cells, the short subunit band is either a proteolytic product of the polypeptide or the product of an alternative translation start site, the two processes may compete for sites, with the highest levels of expression in pancreas, Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MGC22921, O GlcNAc, O GlcNAc transferase p110 subunit, O GlcNAc transferase subunit p110, O linked N acetylglucosamine GlcNAc transferase UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase, O linked N acetylglucosamine transferase 110 kDa subunit, O-GlcNAc transferase, O-GlcNAc transferase subunit p110, O-Linked N-Acetylglucosamine Transferase, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT, OGT1_HUMAN, UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase, HRNT1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
O-GlcNAc transferase |
| Short name: |
O-GlcNAc transferase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
O-GlcNAc transferase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8127 |
| Gene: |
OGT |
More about : OGT |
| Long gene name: |
O-linked N-acetylglucosamine (GlcNAc) transferase |
| Synonyms gene name: |
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) |
| Synonyms: |
O-GLCNAC HRNT1 MGC22921 FLJ23071 |
| Synonyms name: |
UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase |
| Locus: |
Xq13, 1 |
| Discovery year: |
1998-12-03 |
| GenBank acession: |
U77413 |
| Entrez gene record: |
8473 |
| Pubmed identfication: |
9083068 |
| RefSeq identity: |
NM_003605 NM_181672 |
| Classification: |
O-linked N-acetylglucosaminyltransferases Tetratricopeptide repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000033316 |
| Locus Specific Databases: |
Mental Retardation database |