| Long name: |
Biotin Conjugated, MICA+MICB Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MICA+MICB |
| Specificity: |
This is a highly specific antibody against MICA+MICB |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human MICB |
| Gene ID number: |
4277, 100507436 |
| Swiss Prot: |
Q29980, Q29983 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binding to KLRK1 leads to cell lysis, Ligand for the KLRK1/NKG2D receptor, Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PERB11, 1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MICA+MICB Conjugated |
| Short name: |
Conjugated, MICA+MICB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Major histocompabitility complex class I polypeptide-related sequence A+Major histocompabitility complex class I polypeptide-related sequence B (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, MHC class I polypeptide-related sequence B, MICA and IDBG-77578 and ENSG00000204520 and 100507436, MICB and IDBG-77697 and ENSG00000204516 and 4277, PERB11, Plasma membranes, natural killer cell lectin-like receptor binding, protein binding, this GO :0002429 and immune response-activating cell surface receptor signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0009408 and response to heat and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019835 and cytolysis and biological process this GO :0019882 and antigen processing and presentation and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0046629 and gamma-delta T cell activation and biological process this GO :0046703 and natural killer cell lectin-like receptor binding and molecular function this GO :0050689 and negative regulation of defense response to virus by host and biological process this GO :0050776 and regulation of immune response and biological process, this GO :0005515 and protein binding and molecular function this GO :0006955 and immune response and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019882 and antigen processing and presentation and biological process this GO :0045087 and innate immune response and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0046703 : natural killer cell lectin-like receptor binding, this GO :0046703 : natural killer cell lectin-like receptor binding, 2, MHC class I polypeptide-related sequence A |
| Identity: |
7090 |
| Gene: |
MICA |
More about : MICA |
| Long gene name: |
MHC class I polypeptide-related sequence A |
| Locus: |
6p21, 33 |
| Discovery year: |
1994-05-16 |
| GenBank acession: |
L14848 |
| Entrez gene record: |
100507436 |
| Pubmed identfication: |
8022771 |
| RefSeq identity: |
NM_001177519 |
| Classification: |
C1-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031073 |
| Locus Specific Databases: |
IMGT/HLA Database |