| Long name: |
APPD Primary Polyclonal Antibody |
| Also known as: |
APPD PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
APPD |
| Specificity: |
This is a highly specific antibody against APPD |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
75-125/279 |
| Subcellular location: |
Lysosome, Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APPD/ Apoptosis-inducing protein |
| Gene ID number: |
79156 |
| Swiss Prot: |
Q96S99 |
| Tested Applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm, Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8, May induce apoptosis through the lysosomal-mitochondrial pathway |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Apoptosis-inducing protein, LAPF, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, PH and FYVE domain-containing protein 1, PH domain-containing family F member 1, PHAFIN1, PLEKHF1, Phafin-1, Pleckstrin homology domain-containing family F member 1, ZFYVE15, Zinc finger FYVE domain-containing protein 15, APPD |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APPD |
| Short name: |
APPD Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
APPD (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
20764 |
| Gene: |
PLEKHF1 |
More about : PLEKHF1 |
| Long gene name: |
pleckstrin homology and FYVE domain containing 1 |
| Synonyms gene name: |
family F (with FYVE domain) member 1 , pleckstrin homology domain containing |
| Synonyms: |
APPD MGC4090 PHAFIN1 ZFYVE15 |
| Locus: |
19q12 |
| Discovery year: |
2003-04-01 |
| GenBank acession: |
AF434818 |
| Entrez gene record: |
79156 |
| RefSeq identity: |
NM_024310 |
| Classification: |
Pleckstrin homology domain containing Zinc fingers FYVE-type |
| Havana BLAST/BLAT: |
OTTHUMG00000182097 |