| Long name: |
FLIP delta + gamma Primary Polyclonal Antibody |
| Also known as: |
FLIP delta + gamma PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FLIP delta + gamma |
| Specificity: |
This is a highly specific antibody against FLIP delta + gamma |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FLIP delta + gamma |
| Gene ID number: |
8837 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex, Acts as an inhibitor of TNFRSF6 mediated apoptosis, Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis, Lacks enzymatic (caspase) activity, FLIP (or CASP8 and FADD-like apoptosis regulator) is an apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CASP8 and FADD like apoptosis regulator, CFLAR, Caspase like apoptosis regulatory protein, Cellular FLICE like inhibitory protein, FLAME 1, FLAME 1 delta, FLICE, Usurpin gamma |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FLIP delta + gamma |
| Short name: |
FLIP delta + gamma Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FLIP delta and g (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1876 |
| Gene: |
CFLAR |
More about : CFLAR |
| Long gene name: |
CASP8 and FADD like apoptosis regulator |
| Synonyms gene: |
CASP8AP1 |
| Synonyms gene name: |
CASP8 and FADD-like apoptosis regulator |
| Synonyms: |
CASH Casper CLARP FLAME FLIP I-FLICE MRIT c-FLIP |
| Locus: |
2q33, 1 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
AF005774 |
| Entrez gene record: |
8837 |
| Pubmed identfication: |
9208847 9217161 |
| RefSeq identity: |
NM_003879 |
| Classification: |
Endogenous ligands Death effector domain containing Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000132819 |