| Long name: |
Recombinant Cercocebus atys CD40 ligand (CD40LG) |
| Alternative names: |
CD40 ligand, CD40 ligand, CD_antigen: CD154Cleaved into the following 2 chains:CD40 ligand, Tumor necrosis factor ligand superfamily member 5, membrane form, soluble form, CD40 ligand |
| Gene name: |
CD40LG |
| Other gene names: |
CD40-L, CD40L, TNFSF5, CD40LG |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, CD40 ligand(CD40LG) is a recombinant protein expressed in Mammalian Cell |
| Product category: |
Recombinant Proteins |
| Expression system: |
Mammalian Cell |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Gene target: |
Cercocebus atys CD40 ligand (CD40LG) |
| Short name: |
Cercocebus atys CD40 ligand (CD40LG) |
| Alternative name: |
tumor necrosis factor receptor superfamily member 5 ligand (CD40 molecule, tumor necrosis factor receptor superfamily member 5 ligand), Cercocebus atys CD40 molecule |
| Alternative to gene target: |
BT, Bp50 and CDW40 and p50 and TNFRSF5, CD154 and CD40L and gp39 and hCD40L and HIGM1 and IGM and IMD3 and T-BAM and TNFSF5 and TRAP, CD40 and IDBG-78904 and ENSG00000101017 and 958, CD40 ligand, CD40LG and IDBG-631246 and ENSBTAG00000017843 and 282387, CD40LG and IDBG-87653 and ENSG00000102245 and 959, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, Cd40lg and IDBG-147440 and ENSMUSG00000031132 and 21947, Extracellular, Extracellular, TNF receptor superfamily member 5, protein binding, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002768 and immune response-regulating cell surface receptor signaling pathway and biological process this GO :0003823 and antigen binding and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006954 and inflammatory response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0042100 and B cell proliferation and biological process this GO :0042113 and B cell activation and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0043089 and positive regulation of Cdc42 GTPase activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0050776 and regulation of immune response and biological process this GO :0051023 and regulation of immunoglobulin secretion and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0090037 and positive regulation of protein kinase C signaling and biological process this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0003823 : antigen binding, this GO :0003823 : antigen binding and also this GO :0004871 : signal transducer activity and also this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0019899 : enzyme binding and also this GO :0031625 : ubiquitin protein ligase binding, this GO :0004871 : signal transducer activity, this GO :0004872 : receptor activity, this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005174 and CD40 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030168 and platelet activation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0042100 and B cell proliferation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045190 and isotype switching and biological process this GO :0048305 and immunoglobulin secretion and biological process this GO :0050776 and regulation of immune response and biological process this GO :0051023 and regulation of immunoglobulin secretion and biological process this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005174 : CD40 receptor binding and also this GO :0005515 : protein binding, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005174 : CD40 receptor binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0019899 : enzyme binding, this GO :0031625 : ubiquitin protein ligase binding, ubiquitin protein ligase binding, 42498 and IDBG-643036 and ENSBTAG00000020736 and 286849, CD40 molecule |
| Identity: |
11935 |
| Gene: |
CD40LG |
More about : CD40LG |
| Long gene name: |
CD40 ligand |
| Synonyms gene: |
HIGM1 IMD3 TNFSF5 |
| Synonyms gene name: |
member 5 (hyper-IgM syndrome) , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
CD40L TRAP gp39 hCD40L CD154 |
| Synonyms name: |
CD40 antigen ligand tumor necrosis factor (ligand) superfamily member 5 T-B cell-activating molecule TNF-related activation protein hyper-IgM syndrome |
| Locus: |
Xq26, 3 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
X67878 |
| Entrez gene record: |
959 |
| Pubmed identfication: |
1427881 7678782 |
| RefSeq identity: |
NM_000074 |
| Classification: |
Endogenous ligands Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000022512 |
| Locus Specific Databases: |
CD40Lbase: Mutation registry for X-linked Hyper-IgM syndrome Mental Retardation database LRG_141 |