Lin-28 Antibody, ALEXA FLUOR 350

Catalog number:	bs-6446R-A350 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Lin-28 Antibody, ALEXA FLUOR 350
Quantity:	100ul
Related search:	lin antibody gene pre conjugated terminal leading

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Long name:	ALEXA FLUOR 350 Conjugated, Lin-28 Polyclonal Antibody
Also known as:	Anti-Lin-28 PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Lin-28
Specificity:	This is a highly specific antibody against Lin-28
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	70-120/250
Subcellular location:	Nucleus, Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lin-28B
Gene ID Number:	79727, 389421
Swiss Prot:	Q6ZN17, Q9H9Z2
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, Isoform 1, Isoform 2 has no effect on cell growth, Mediates MYC-mediated let-7 repression, Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7, Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation, a miRNA precursor, leading to the terminal uridylation of pre-let-7, leading to their terminal uridylation and subsequent degradation, stimulates growth of the breast adenocarcinoma cell line MCF-7, when overexpressed, Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7)
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Synonyms:	LIN-28 FLJ12457 ZCCHC1 CSDD1
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	Lin-28
Short name:	Lin-28 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, Lin-28 (Antibody to)
Alternative technique:	antibodies
Identity:	15986
Gene:	LIN28A | More about : LIN28A
Long gene name:	lin-28 homolog A
Synonyms gene:	LIN28
Synonyms gene name:	elegans) , lin-28 homolog (C
Locus:	1p36, 11
Discovery year:	2003-07-21
GenBank acession:	AF521099
Entrez gene record:	79727
Pubmed identfication:	12798299
RefSeq identity:	NM_024674
Classification:	Zinc fingers CCHC-type
Havana BLAST/BLAT:	OTTHUMG00000003550

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