| Long name: |
Recombinant Human Endothelin-1 (EDN1) |
| Alternative names: |
Endothelin-1, Preproendothelin-1, endothelin 1, endothelin-1, preproendothelin-1, endothelin-1 isoform 2 preproprotein |
| Other gene names: |
EDN1, ET-1, ET1, HDLCQ7, PPET1, PPET1, EDN1 |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Endothelin-1 (EDN1) is a recombinant protein expressed in Yeast |
| Product category: |
Recombinant Proteins |
| Expression system: |
Yeast |
| Available also expressed in:: |
Yeast, E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
We can custom produce according to your specifications, This item requires custom production and lead time is between 5-9 weeks |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
Endothelin-1 (EDN1) |
| Short name: |
Endothelin-1 (EDN1) |
| Species: |
Humans, Human |
| Alternative name: |
sapiens Endothelin-1 (endothelin 1), H |
| Alternative to gene target: |
ARCND3 and ET1 and HDLCQ7 and PPET1 and QME, EDN1 and IDBG-61847 and ENSG00000078401 and 1906, EDN1 and IDBG-636110 and ENSBTAG00000008096 and 281137, Edn1 and IDBG-147056 and ENSMUSG00000021367 and 13614, Extracellular, endothelin B receptor binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001501 and skeletal system development and biological process this GO :0001516 and prostaglandin biosynthetic process and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001821 and histamine secretion and biological process this GO :0003100 and regulation of systemic arterial blood pressure by endothelin and biological process this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006885 and regulation of pH and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007205 and protein kinase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007507 and heart development and biological process this GO :0007585 and respiratory gaseous exchange and biological process this GO :0007589 and body fluid secretion and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0010193 and response to ozone and biological process this GO :0010259 and multicellular organismal aging and biological process this GO :0010460 and positive regulation of heart rate and biological process this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0010613 and positive regulation of cardiac muscle hypertrophy and biological process this GO :0010870 and positive regulation of receptor biosynthetic process and biological process this GO :0014032 and neural crest cell development and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0014823 and response to activity and biological process this GO :0014824 and artery smooth muscle contraction and biological process this GO :0014826 and vein smooth muscle contraction and biological process this GO :0015758 and glucose transport and biological process this GO :0016049 and cell growth and biological process this GO :0019229 and regulation of vasoconstriction and biological process this GO :0019233 and sensory perception of pain and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0030072 and peptide hormone secretion and biological process this GO :0030185 and nitric oxide transport and biological process this GO :0030195 and negative regulation of blood coagulation and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030818 and negative regulation of cAMP biosynthetic process and biological process this GO :0031583 and phospholipase D-activating G-protein coupled receptor signaling pathway and biological process this GO :0031707 and endothelin A receptor binding and molecular function this GO :0031708 and endothelin B receptor binding and molecular function this GO :0032269 and negative regulation of cellular protein metabolic process and biological process this GO :0032308 and positive regulation of prostaglandin secretion and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033093 and Weibel-Palade body and cellular component this GO :0033574 and response to testosterone and biological process this GO :0034392 and negative regulation of smooth muscle cell apoptotic process and biological process this GO :0034696 and response to prostaglandin F and biological process this GO :0035094 and response to nicotine and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035690 and cellular response to drug and biological process this GO :0035810 and positive regulation of urine volume and biological process this GO :0035815 and positive regulation of renal sodium excretion and biological process this GO :0035994 and response to muscle stretch and biological process this GO :0042045 and epithelial fluid transport and biological process this GO :0042310 and vasoconstriction and biological process this GO :0042313 and protein kinase C deactivation and biological process this GO :0042474 and middle ear morphogenesis and biological process this GO :0042482 and positive regulation of odontogenesis and biological process this GO :0042493 and response to drug and biological process this GO :0042554 and superoxide anion generation and biological process this GO :0043179 and rhythmic excitation and biological process this GO :0043200 and response to amino acid and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0044321 and response to leptin and biological process this GO :0045087 and innate immune response and biological process this GO :0045178 and basal part of cell and cellular component this GO :0045321 and leukocyte activation and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045793 and positive regulation of cell size and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045987 and positive regulation of smooth muscle contraction and biological process this GO :0046887 and positive regulation of hormone secretion and biological process this GO :0046888 and negative regulation of hormone secretion and biological process this GO :0048016 and inositol phosphate-mediated signaling and biological process this GO :0048237 and rough endoplasmic reticulum lumen and cellular component this GO :0048514 and blood vessel morphogenesis and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0051216 and cartilage development and biological process this GO :0051482 and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway and biological process this GO :0051771 and negative regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0051899 and membrane depolarization and biological process this GO :0051930 and regulation of sensory perception of pain and biological process this GO :0060137 and maternal process involved in parturition and biological process this GO :0060298 and positive regulation of sarcomere organization and biological process this GO :0060585 and positive regulation of prostaglandin-endoperoxide synthase activity and biological process this GO :0070101 and positive regulation of chemokine-mediated signaling pathway and biological process this GO :0071277 and cellular response to calcium ion and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071375 and cellular response to peptide hormone stimulus and biological process this GO :0071385 and cellular response to glucocorticoid stimulus and biological process this GO :0071389 and cellular response to mineralocorticoid stimulus and biological process this GO :0071398 and cellular response to fatty acid and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071548 and response to dexamethasone and biological process this GO :0071559 and response to transforming growth factor beta and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process this GO :1902074 and response to salt and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005179 : hormone activity and also this GO :0005515 : protein binding and also this GO :0031707 : endothelin A receptor binding and also this GO :0031708 : endothelin B receptor binding, this GO :0005125 : cytokine activity, this GO :0005179 : hormone activity, this GO :0005515 : protein binding, this GO :0031707 : endothelin A receptor binding, this GO :0031708 : endothelin B receptor binding, endothelin 1 |
| Identity: |
3176 |
| Gene: |
EDN1 |
More about : EDN1 |
| Long gene name: |
endothelin 1 |
| Synonyms: |
ET1 |
| Locus: |
6p24, 1 |
| Discovery year: |
1989-04-06 |
| GenBank acession: |
S56805 |
| Entrez gene record: |
1906 |
| RefSeq identity: |
NM_001955 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000014266 |