| Long name: |
Biotin Conjugated, Complement fragment 3c Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Complement fragment 3c |
| Specificity: |
This is a highly specific antibody against Complement fragment 3c |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1 |
| Gene ID number: |
718 |
| Swiss Prot: |
P01024 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Mouse, Pig, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ARRB2-mediated internalization and recycling of C5AR2 (PubMed:837664, Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, After activation C3b can bind covalently, Appears to stimulate TG synthesis via activation of the PLC, C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation, C3a anaphylatoxin is a mediator of local inflammatory process, Derived from proteolytic degradation of complement C3, In chronic inflammation, It induces the contraction of smooth muscle, Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways, Ligand for C5AR2, MAPK and AKT signaling pathways, Promotes the phosphorylation, PubMed:1432298, PubMed:15833747, PubMed:16333141, PubMed:1961575), PubMed:29953, PubMed:959512, acts as a chemoattractant for neutrophils (By similarity), increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes, regulating fat storage and playing a role in postprandial TG clearance, to cell surface carbohydrates or immune aggregates, via its reactive thioester, C3 plays a central role in the activation of the complement system |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
AHUS5, ARMD9, C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3a, C3b, CPAMD1, Complement C3, HEL-S-62p, ASP |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Complement 3c Conjugated |
| Short name: |
Conjugated, Complement 3c Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Isotype: |
Complement fragments, Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small, IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion, bp DNA fragments are common, coli expressed, single chain variable fragments can be E, Antibody fragments and scFv fragments |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Complement fragment 3c (Antibody to) |
| Alternative technique: |
antibodies |