| Long name: |
NTR3 Primary Polyclonal Antibody |
| Also known as: |
NTR3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NTR3 |
| Specificity: |
This is a highly specific antibody against NTR3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
705-755/831 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sortilin |
| Gene ID number: |
6272 |
| Swiss Prot: |
Q99523 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also acts as a receptor for neurotensin, Also required for protein transport from the Golgi apparatus to the endosomes, May also mediate transport from the endoplasmic reticulum to the Golgi, May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL, Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB), Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR), These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin, or GSVs), Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
100 kDa NT receptor, Glycoprotein 95, Gp95, LDLCQ6, NTR3, Neurotensin receptor 3, SORT1, Sortilin, NT3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NTR3 |
| Short name: |
NTR3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NTR3 (Antibody to) |
| Alternative technique: |
antibodies |