| Long name: |
Ryanodine Receptor Primary Polyclonal Antibody |
| Also known as: |
Ryanodine Receptor PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Ryanodine Receptor |
| Specificity: |
Ryanodine Receptor 2, This antibody will recognize Ryanodine Receptor 1, and Ryanodine Receptor 3, This is a highly specific antibody against Ryanodine Receptor |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
4700-4750/5038 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ryanodine Receptor |
| Gene ID number: |
6261, 6262, 6263 |
| Swiss Prot: |
Q15413, Q92736, P21817 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In non-mammalian vertebrates, Mammalian RyR isoforms are the product of three different genes: RyR-1 is expressed predominantly in skeletal muscle and areas of the brain, RyR-2 is expressed predominantly in heart muscle but also found in the stomach, RyR-3 and RyR-2 isoforms respectively, The RyR exists as a homotetramer and is predicted to have a short cytoplasmic C-terminus and 4-10 transmembrane domains, The remainder of the protein, and RyR-3 is found in smooth muscle and the brain (striatum, beta and cardiac which correlate loosely to the mammalian RyR-1, endothelial cells and diffuse areas of the brain, is located in the cytoplasm between the transverse tubule and the SR, region, termed the ", thalamus and hippocampus), the RyR isoforms are termed alpha, The Ryanodine Receptor (RyR) is the channel responsible for calcium release from muscle cell Sarcoplasmic Reticulum (SR) and also plays a role in calcium regulation in non-muscle cells, foot" |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ARVC 2, ARVC2, ARVD 2, ARVD2, Brain ryanodine receptor calcium release channel, Brain type ryanodine receptor, CCO, Cardiac muscle ryanodine receptor, Cardiac muscle ryanodine receptor calcium release channel, Cardiac muscle type ryanodine receptor, Central core disease of muscle, HBRR, MHS, MHS1, RYDR, RYR, RYR 1, RYR 2, RYR 3, RYR1, RYR2, RYR3, Ryanodine receptor 1, Ryanodine receptor 1 skeletal, Ryanodine receptor 2, Ryanodine receptor 2 cardiac, Ryanodine receptor 3, Ryanodine receptor type1, SKRR, Sarcoplasmic reticulum calcium release channel, Skeletal muscle calcium release channel, Skeletal muscle ryanodine receptor, Skeletal muscle type ryanodine receptor, Type 1 like ryanodine receptor, VTSIP, hRYR 2, hRYR2, Arrhythmogenic right ventricular dysplasia 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Ryanodine Receptor |
| Short name: |
Ryanodine Receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Ryanodine Receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10485 |
| Gene: |
RYR3 |
More about : RYR3 |
| Long gene name: |
ryanodine receptor 3 |
| Locus: |
15q13, 3-q14 |
| Discovery year: |
1993-05-12 |
| Entrez gene record: |
6263 |
| Pubmed identfication: |
8276408 |
| Classification: |
Ryanodine receptors EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000172253 |