| Long name: |
FITC Conjugated, CD109 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CD109 |
| Specificity: |
This is a highly specific antibody against CD109 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
920-970/1145 |
| Subcellular location: |
Cell membrane |
| Source: |
KLH conjugated synthetic peptide derived from human CD109 |
| Gene ID number: |
135228 |
| Swiss Prot: |
Q6YHK3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Although it has been suggested that T-cell CD109 may play a role in antibody-inducing T-helper function and it is known that platelet CD109 carries the Gov alloantigen system, It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170 kd found onendothelial cells, activated platelets and T-cells and on a subset of hematopoietic stem and progenitor cells, the role of CD109 in hematopoietic cells remains largely unknown, CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes and upregulation of CD109 expression has been observed in several different types of tumour, CD109 is a a novel member of the alpha2-macroglobulin (alpha2M)/complement superfamily |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FLJ38569 DKFZp762L1111 CPAMD7 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CD109 Conjugated |
| Short name: |
FITC Conjugated, CD109 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CD109 molecule (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD109 and IDBG-629598 and ENSBTAG00000013222 and 534043, CD109 and IDBG-92570 and ENSG00000156535 and 135228, Cd109 and IDBG-187096 and ENSMUSG00000046186 and 235505, Extracellular, this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0061045 and negative regulation of wound healing and biological process, this GO :0004866 : endopeptidase inhibitor activity, this GO :0004866 : endopeptidase inhibitor activity and also this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0050431 : transforming growth factor beta binding, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0050431 : transforming growth factor beta binding, transforming growth factor beta binding, CD109 molecule |
| Identity: |
21685 |
| Gene: |
CD109 |
More about : CD109 |
| Long gene name: |
CD109 molecule |
| Synonyms gene name: |
CD109 antigen (Gov platelet alloantigens) |
| Locus: |
6q13 |
| Discovery year: |
2003-07-04 |
| GenBank acession: |
AF410459 |
| Entrez gene record: |
135228 |
| Pubmed identfication: |
11861284 11861285 |
| RefSeq identity: |
NM_133493 |
| Classification: |
CD molecules C3 and PZP like, alpha-2-macroglobulin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015040 |
| Locus Specific Databases: |
LRG_1002 |