| Long name: |
FITC Conjugated, MAS1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MAS1 |
| Specificity: |
This is a highly specific antibody against MAS1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
70-120/325 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human MAS1 |
| Gene ID number: |
4142 |
| Swiss Prot: |
P04201 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1, although it up-regulates AGTR1 receptor levels, and stimulation of the protein kinase C signaling cascade, Receptor for angiotensin 1-7 (By similarity) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MAS1 Conjugated |
| Short name: |
FITC Conjugated, MAS1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, MAS1 oncogene (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, MAS and MGRA, MAS1 and IDBG-647063 and ENSBTAG00000031724 and 783010, MAS1 and IDBG-98585 and ENSG00000130368 and 4142, Mas1 and IDBG-137347 and ENSMUSG00000068037 and 17171, peptide binding, this GO :0001595 and angiotensin receptor activity and molecular function this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004945 and angiotensin type II receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008584 and male this GO nad development and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0009986 and cell surface and cellular component this GO :0014823 and response to activity and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0017046 and peptide hormone binding and molecular function this GO :0021766 and hippocampus development and biological process this GO :0034698 and response to this GO nadotropin and biological process this GO :0038166 and angiotensin-activated signaling pathway and biological process this GO :0042277 and peptide binding and molecular function this GO :0042493 and response to drug and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0060732 and positive regulation of inositol phosphate biosynthetic process and biological process this GO :0070528 and protein kinase C signaling and biological process this GO :0071375 and cellular response to peptide hormone stimulus and biological process, this GO :0001595 : angiotensin receptor activity, this GO :0001595 : angiotensin receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004945 : angiotensin type II receptor activity and also this GO :0017046 : peptide hormone binding and also this GO :0042277 : peptide binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0004945 : angiotensin type II receptor activity, this GO :0017046 : peptide hormone binding, this GO :0042277 : peptide binding, MAS1 oncogene |
| Identity: |
6899 |
| Gene: |
MAS1 |
More about : MAS1 |
| Long gene name: |
G protein-coupled receptor , MAS1 proto-oncogene |
| Synonyms gene name: |
MAS1 oncogene |
| Locus: |
6q25, 3 |
| Discovery year: |
1988-07-04 |
| GenBank acession: |
M13150 |
| Entrez gene record: |
4142 |
| RefSeq identity: |
NM_002377 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000015944 |