| Long name: |
PATZ1 Primary Polyclonal Antibody |
| Also known as: |
PATZ1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PATZ1 |
| Specificity: |
This is a highly specific antibody against PATZ1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
370-420/687 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PATZ1 |
| Gene ID number: |
23598 |
| Swiss Prot: |
Q9HBE1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Four alternatively spliced transcript variants are described for this gene, In small round cell sarcoma, Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, Jul 2008], Since the encoded protein has typical features of a transcription factor, The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein, This is a distinct example of an intra-chromosomal rearrangement of chromosome 22, [provided by RefSeq, and the zinc-fingers comprise the DNA binding domain, it is postulated to be a repressor of gene expression, then the hybrid is thought to be translocated (t(1, this gene is fused to EWS by a small inversion of 22q, 1, 22)(p36, The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation, q12) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AT hook-, BTB/POZ domain zinc finger transcription factor, PATZ, PATZ1, Protein kinase A RI subunit alpha-associated protein, RIAZ, ZBTB19, ZNF278, ZSG, Zinc finger and BTB domain-containing protein 19, Zinc finger protein 278, Zinc finger sarcoma gene protein, and zinc finger-containing protein 1, POZ- |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PATZ1 |
| Short name: |
PATZ1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
POZ (BTB) and AT hook containing zinc finger 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008584 and male this GO nad development and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0030217 and T cell differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function, PATZ1 and IDBG-4572 and ENSG00000100105 and 23598, PATZ1 and IDBG-636698 and ENSBTAG00000005478 and 532416, Patz1 and IDBG-138937 and ENSMUSG00000020453 and 56218, dJ400N23 and MAZR and PATZ and RIAZ and ZBTB19 and ZNF278 and ZSG, metal ion binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0005515 : protein binding and also this GO :0046872 : metal ion binding, this GO :0003682 : chromatin binding, this GO :0005515 : protein binding, this GO :0046872 : metal ion binding, POZ (BTB) and AT hook containing zinc finger 1 |
| Identity: |
13071 |
| Gene: |
PATZ1 |
More about : PATZ1 |
| Long gene name: |
POZ/BTB and AT hook containing zinc finger 1 |
| Synonyms gene: |
ZNF278 |
| Synonyms gene name: |
zinc finger protein 278 POZ (BTB) and AT hook containing zinc finger 1 |
| Synonyms: |
MAZR dJ400N23 ZBTB19 ZSG RIAZ PATZ |
| Locus: |
22q12, 2 |
| Discovery year: |
1999-10-20 |
| GenBank acession: |
AL096880 |
| Entrez gene record: |
23598 |
| Pubmed identfication: |
10591208 18241078 18401526 |
| RefSeq identity: |
NM_032052 |
| Classification: |
BTB domain containing Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000151254 |