| Long name: |
ALEXA FLUOR 350 Conjugated, ANGPTL3 Polyclonal Antibody |
| Also known as: |
Anti-ANGPTL3 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ANGPTL3 |
| Specificity: |
This is a highly specific antibody against ANGPTL3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
40-90/460 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3 |
| Gene ID Number: |
27329 |
| Swiss Prot: |
Q9Y5C1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A deficiency of Angptl3 results in abnormally low lipid levels, Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3), Angptl3 may also play an important role in hyperlipidemia in diabetes, Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle, It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain, and a repression of the protein may be protective against atherosclerosis, Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
ANGPTL3 |
| Short name: |
ANGPTL3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, angiopoietin-like 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ANGPTL3 and IDBG-638594 and ENSBTAG00000021386 and 782603, ANGPTL3 and IDBG-99367 and ENSG00000132855 and 27329, Angptl3 and IDBG-166252 and ENSMUSG00000028553 and 30924, Extracellular, growth factor activity, this GO :0004857 and enzyme inhibitor activity and molecular function this GO :0004859 and phospholipase inhibitor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006071 and glycerol metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0009395 and phospholipid catabolic process and biological process this GO :0009725 and response to hormone and biological process this GO :0009986 and cell surface and cellular component this GO :0010519 and negative regulation of phospholipase activity and biological process this GO :0019915 and lipid storage and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050996 and positive regulation of lipid catabolic process and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0055090 and acylglycerol homeostasis and biological process this GO :0055091 and phospholipid homeostasis and biological process this GO :0070328 and triglyceride homeostasis and biological process, this GO :0004857 : enzyme inhibitor activity, this GO :0004857 : enzyme inhibitor activity and also this GO :0004859 : phospholipase inhibitor activity and also this GO :0005178 : integrin binding and also this GO :0008083 : growth factor activity, this GO :0004859 : phospholipase inhibitor activity, this GO :0005178 : integrin binding, this GO :0008083 : growth factor activity, angiopoietin-like 3 |
| Identity: |
491 |
| Gene: |
ANGPTL3 |
More about : ANGPTL3 |
| Long gene name: |
angiopoietin like 3 |
| Synonyms gene: |
ANGPT5 |
| Synonyms gene name: |
angiopoietin-like 3 |
| Synonyms name: |
angiopoietin 5 |
| Locus: |
1p31, 3 |
| Discovery year: |
2000-02-07 |
| GenBank acession: |
AF152562 |
| Entrez gene record: |
27329 |
| Pubmed identfication: |
10644446 |
| RefSeq identity: |
NM_014495 |
| Classification: |
Fibrinogen C domain containing Angiopoietin like |
| Havana BLAST/BLAT: |
OTTHUMG00000009146 |