| Long name: |
KLKB1 Primary Polyclonal Antibody |
| Also known as: |
KLKB1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
KLKB1 |
| Specificity: |
This is a highly specific antibody against KLKB1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLKB1/Plasma Kallikrein 1B |
| Gene ID number: |
3818 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Each repeat harbors a novel structure called the apple domain, It is synthesized in the liver and secreted into the blood as a single polypeptide chain, Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond, Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients, Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond, The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein, The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids, The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases, fibrinolysis, kinin generation and inflammation, Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Fletcher factor, KLK3, KLKB1, KLKB1_HUMAN, Kallikrein 3 plasma Fletcher factor, Kallikrein B, Kallikrein B plasma Fletcher factor 1, Kininogenin, PPK, Plasma kallikrein, Plasma kallikrein B1, Plasma kallikrein light chain, Plasma prekallikrein, Prekallikrein, kallikrein B plasma, plasma 1, 4, 21, 34, EC 3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
KLKB1 |
| Short name: |
KLKB1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
KLKB1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6371 |
| Gene: |
KLKB1 |
More about : KLKB1 |
| Long gene name: |
kallikrein B1 |
| Synonyms gene: |
KLK3 |
| Synonyms gene name: |
kallikrein B, plasma (Fletcher factor) 1 |
| Synonyms name: |
Fletcher factor |
| Locus: |
4q35, 2 |
| Discovery year: |
1999-04-23 |
| GenBank acession: |
M13143 |
| Entrez gene record: |
3818 |
| Pubmed identfication: |
9535413 3521732 |
| RefSeq identity: |
NM_000892 |
| Classification: |
Kallikreins |
| Havana BLAST/BLAT: |
OTTHUMG00000150347 |