| Long name: |
PDGFC Primary Polyclonal Antibody |
| Also known as: |
PDGFC PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PDGFC |
| Specificity: |
This is a highly specific antibody against PDGFC |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
240-290/345 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDGFC/VEGF E |
| Gene ID number: |
56034 |
| Swiss Prot: |
Q9NRA1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In the nucleus, Involved in fibrotic processes, PDGFC seems to have additional function, Plays an important role in angiogenesis and blood vessel development, Plays an important role in wound healing, Potent mitogen and chemoattractant for cells of mesenchymal origin, Required for normal skeleton formation during embryonic development, Required for normal skin morphogenesis during embryonic development, The CUB domain has mitogenic activity in coronary artery smooth muscle cells, cell migration, cell proliferation, especially for normal development of the craniofacial skeleton and for normal development of the palate, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs, proliferation and remodeling, suggesting a role beyond the maintenance of the latency of the PDGF domain, survival and chemotaxis, where it appears to be involved in three stages: inflammation, Growth factor that plays an essential role in the regulation of embryonic development |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FALLOTEIN, PDGF-C, PDGFC, Platelet-derived growth factor C, Spinal cord-derived growth factor, UNQ174/PRO2, VEGF-E, SCDGF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PDGFC |
| Short name: |
PDGFC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
platelet derived growth factor C (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PDGFC and IDBG-42546 and ENSG00000145431 and 56034, PDGFC and IDBG-630627 and ENSBTAG00000043959 and 613787, Pdgfc and IDBG-153854 and ENSMUSG00000028019 and 54635, nuclei, protein homodimerization activity, this GO :0000139 and this GO lgi membrane and cellular component this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007417 and central nervous system development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0042803 and protein homodimerization activity and molecular function this GO :0045740 and positive regulation of DNA replication and biological process this GO :0048008 and platelet-derived growth factor receptor signaling pathway and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0050730 and regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071230 and cellular response to amino acid stimulus and biological process, this GO :0005161 : platelet-derived growth factor receptor binding, this GO :0005161 : platelet-derived growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0042803 : protein homodimerization activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0042803 : protein homodimerization activity, platelet derived growth factor C |
| Identity: |
8801 |
| Gene: |
PDGFC |
More about : PDGFC |
| Long gene name: |
platelet derived growth factor C |
| Synonyms: |
SCDGF fallotein |
| Locus: |
4q32, 1 |
| Discovery year: |
2000-07-31 |
| GenBank acession: |
AF091434 |
| Entrez gene record: |
56034 |
| Pubmed identfication: |
10858496 |
| Havana BLAST/BLAT: |
OTTHUMG00000161803 |