| Long name: |
MBNL3 Primary Polyclonal Antibody |
| Also known as: |
MBNL3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MBNL3 |
| Specificity: |
This is a highly specific antibody against MBNL3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MBNL3 |
| Gene ID number: |
55796 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
MBNL proteins have been shown to sequester foci of expanded-repeat transcripts and are thought to therefore play a role in the molecular pathology of a group of neuromuscular diseases including the Myotonic Dystrophies, MBNL3 belongs to a highly conserved family of tissue-specific alternative splicing regulators, MBNL3 is expressed in myoblasts, This family is known to regulate terminal muscle differentiation through alternative splicing control and several groups have suggested that the family participates in the differentiation of photoreceptors, adipocytes and blood cell types, and during the early stages of myogenesis, but is detected at very low levels in terminally differentiated myotubes, muscle precursor cells, neurons, MBNL3 has been shown to inhibit muscle differentiation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CHCR, Cys3His CCG1 required protein, MBLX39, MBNL 3, MBNL3_HUMAN, MBXL, Muscleblind like X linked protein, Muscleblind like protein 3, Protein HCHCR, MBLX |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MBNL3 |
| Short name: |
MBNL3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MBNL3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
20564 |
| Gene: |
MBNL3 |
More about : MBNL3 |
| Long gene name: |
muscleblind like splicing regulator 3 |
| Synonyms gene name: |
muscleblind-like 3 (Drosophila) muscleblind-like splicing regulator 3 |
| Synonyms: |
CHCR FLJ11316 MBLX39 MBXL |
| Locus: |
Xq26, 2 |
| Discovery year: |
2003-03-05 |
| GenBank acession: |
AF491305 |
| Entrez gene record: |
55796 |
| Pubmed identfication: |
12297108 10970838 |
| RefSeq identity: |
NM_018388 |
| Classification: |
Zinc fingers CCCH-type |
| Havana BLAST/BLAT: |
OTTHUMG00000022426 |
| Locus Specific Databases: |
Mental Retardation database |