| Long name: |
Biotin Conjugated, HOXA5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HOXA5 |
| Specificity: |
This is a highly specific antibody against HOXA5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HOXA5 |
| Gene ID number: |
3202 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
HOXA5 expression is an important step in tumorigenesis and loss of expression of p53 in human breast cancer may be primarily due to lack of expression of HOXA5, HOXA5 is detectable in approximately one-third of primary tumors, Lack of HOXA5 expression strongly correlates with methylation of its promoter region, leading to apoptosis, suggesting a causal role for methylation in the silencing of HOXA5 gene expression, HOXA5 upregulates both p53 promoter-reporter constructs and endogenous p53 synthesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HOXA5 Conjugated |
| Short name: |
Conjugated, HOXA5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, homeobox A5 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0007389 and pattern specification process and biological process this GO :0007585 and respiratory gaseous exchange and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0010870 and positive regulation of receptor biosynthetic process and biological process this GO :0016477 and cell migration and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0030324 and lung development and biological process this GO :0030878 and thyroid gland development and biological process this GO :0033599 and regulation of mammary gland epithelial cell proliferation and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045639 and positive regulation of myeloid cell differentiation and biological process this GO :0045647 and negative regulation of erythrocyte differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048704 and embryonic skeletal system morphogenesis and biological process this GO :0048706 and embryonic skeletal system development and biological process this GO :0060435 and bronchiole development and biological process this GO :0060439 and trachea morphogenesis and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process this GO :0060480 and lung this GO blet cell differentiation and biological process this GO :0060481 and lobar bronchus epithelium development and biological process this GO :0060484 and lung-associated mesenchyme development and biological process this GO :0060535 and trachea cartilage morphogenesis and biological process this GO :0060536 and cartilage morphogenesis and biological process this GO :0060574 and intestinal epithelial cell maturation and biological process this GO :0060638 and mesenchymal-epithelial cell signaling and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0060764 and cell-cell signaling involved in mammary gland development and biological process, HOX1 and HOX1, HOXA5 and IDBG-10422 and ENSG00000106004 and 3202, HOXA5 and IDBG-633592 and ENSBTAG00000012211 and 768039, Hoxa5 and IDBG-147940 and ENSMUSG00000038253 and 15402, nuclei, sequence-specific DNA binding, this GO :0001501 and skeletal system development and biological process this GO :0002009 and morphogenesis of an epithelium and biological process this GO :0003016 and respiratory system process and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, 3 and HOX1C, homeobox A5 |
| Identity: |
5106 |
| Gene: |
HOXA5 |
More about : HOXA5 |
| Long gene name: |
homeobox A5 |
| Synonyms gene: |
HOX1C HOX1 |
| Synonyms gene name: |
homeo box A5 |
| Locus: |
7p15, 2 |
| Discovery year: |
1990-06-15 |
| Entrez gene record: |
3202 |
| Pubmed identfication: |
1973146 1358459 |
| Classification: |
HOXL subclass homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000023214 |