| Long name: |
ALEXA FLUOR 488 Conjugated, TNIK (Ser764) Polyclonal Antibody |
| Also known as: |
Anti-TNIK Ser764 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TNIK Ser764 |
| Specificity: |
This is a highly specific antibody against TNIK Ser764 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser764 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
759-766/1360 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764 |
| Gene ID Number: |
23043 |
| Swiss Prot: |
Q9UKE5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Appears to act upstream of the JUN N-terminal pathway, May act by phosphorylating TCF4/TCF7L2, May play a role in the response to environmental stress, More generally, Part of a signaling complex composed of NEDD4, Phosphorylates SMAD1 on Thr-322, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development, Recruited to promoters of Wnt target genes and required to activate their expression, it may play a role in cytoskeletal rearrangements and regulate cell spreading, Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
KIAA0551 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TNIK (Ser764) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TNIK (Ser764) |
| Short name: |
TNIK (Ser764) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, TRAF2 and NCK interacting kinase (Ser764) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627, TNIK and IDBG-64741 and ENSG00000154310 and 23043, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007256 and activation of JNKK activity and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005083 : small GTPase regulator activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005083 : small GTPase regulator activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048814 and regulation of dendrite morphogenesis and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, TRAF2 and NCK interacting kinase |
| Identity: |
30765 |
| Gene: |
TNIK |
More about : TNIK |
| Long gene name: |
TRAF2 and NCK interacting kinase |
| Locus: |
3q26, 2-q26, 31 |
| Discovery year: |
2004-02-26 |
| GenBank acession: |
AF172264 |
| Entrez gene record: |
23043 |
| Pubmed identfication: |
9628581 10521462 |
| RefSeq identity: |
XM_039796 |
| Havana BLAST/BLAT: |
OTTHUMG00000159036 |