| Long name: |
ALEXA FLUOR 350 Conjugated, TNIK Polyclonal Antibody |
| Also known as: |
Anti-TNIK PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TNIK |
| Specificity: |
This is a highly specific antibody against TNIK |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TNIK |
| Gene ID Number: |
23043 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ESTs have been isolated from human tissue libraries, Northern analysis indicates TNIK expression in human heart, TNIK has been shown to phosphorylate gelsolin, The protein has been shown to activate the c-Jun N-terminal kinase pathway when over expressed in Phoenix-A cells, This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton, and brain, and pancreas, gallbladder and skin, in vitro, including normal amnion, liver, lung, skeletal muscle, the principal intracellular and extracellular actin-severing protein, with lower levels of expression in kidney, TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
KIAA0551 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
TNIK |
| Short name: |
TNIK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, TRAF2 and NCK interacting kinase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627, TNIK and IDBG-64741 and ENSG00000154310 and 23043, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007256 and activation of JNKK activity and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005083 : small GTPase regulator activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005083 : small GTPase regulator activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048814 and regulation of dendrite morphogenesis and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, TRAF2 and NCK interacting kinase |
| Identity: |
30765 |
| Gene: |
TNIK |
More about : TNIK |
| Long gene name: |
TRAF2 and NCK interacting kinase |
| Locus: |
3q26, 2-q26, 31 |
| Discovery year: |
2004-02-26 |
| GenBank acession: |
AF172264 |
| Entrez gene record: |
23043 |
| Pubmed identfication: |
9628581 10521462 |
| RefSeq identity: |
XM_039796 |
| Havana BLAST/BLAT: |
OTTHUMG00000159036 |