| Long name: |
PI 3 Kinase p110 delta (Tyr524) Antibody |
| Also known as: |
PI 3 Kinase p110 delta (Tyr524) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PI 3 Kinase p110 delta Tyr524 |
| Specificity: |
This is a highly specific antibody against PI 3 Kinase p110 delta Tyr524 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr524 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
510-545/1044 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PIK3CD around the phosphorylation site of Tyr524 |
| Gene ID number: |
5293 |
| Swiss Prot: |
O00329 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activation by TCR leads to antigen-dependent memory T-cell migration and retention to antigenic tissues, CCR7 and S1PR1 and antigen dependent recruitment of T-cells, Contributes to T-helper cell expansion and differentiation, Have a role in NK cell maturation and cytokine production, Have important roles in mast-cell development and mast cell mediated allergic response, Involved in B-cell chemotaxis in response to CXCL13 and sphingosine 1-phosphate (S1P), Involved in stem cell factor (SCF)-mediated proliferation, Involved in the antigen presentation function of B-cells, Mediates B-cell proliferation response to anti-IgM, Mediates TCR signaling events at the immune synapse, Mediates immune responses, PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, Participates in NK cell receptor activation, Plays a role in B-cell development, Promotes cytokine production in response to TLR4 and TLR9, Required for B-cell receptor (BCR) signaling, Required for T-cell migration mediated by homing receptors SELL/CD62L, Required for T-cell receptor (TCR) signaling, Required for antibody class switch mediated by TLR9, Required for proliferation, Together with PIK3CG is involved in natural killer (NK) cell development and migration towards the sites of inflammation, Together with PIK3CG is involved in neutrophil chemotaxis and extravasation, Together with PIK3CG participates in T-cell development, Together with PIK3CG participates in neutrophil respiratory burst, activating signaling cascades involved in cell growth, adhesion and migration, and function, anti-CD40 and IL4 stimulation, effector and memory T-cells, including AKT1 and PDPK1, migration, motility and morphology, proliferation, proliferation, signaling and cytokine production of naive, survival, 4, 5)P2 (Phosphatidylinositol 4, 5-bisphosphate) to generate phosphatidylinositol 3, 5-trisphosphate (PIP3), Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PIK3CD, Phosphatidylinositol 4, PtdIns-3-kinase subunit delta, PtdIns-3-kinase subunit p110-delta, p110delta, 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, 5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PI 3 Kinase p110 delta (Tyr524) |
| Short name: |
PI 3 Kinase p110 delta (Tyr524) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PI 3 phosphorylation catalyst p110 delta (Tyr524) (Antibody to) |
| Alternative technique: |
antibodies |