| Long name: |
Biotin Conjugated, IKB epsilon (Ser157) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IKB epsilon Ser157 |
| Specificity: |
This is a highly specific antibody against IKB epsilon Ser157 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser157 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human NFKBIE around the phosphorylation site of Ser157 |
| Gene ID number: |
4794 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AP1 (JUN), Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, For some genes, Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, R is an A or G purine, RELA, The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, activation requires NFKB interaction with other transcription factors, and NFAT, and Y is a C or T pyrimidine), or IKBKB) marks them for destruction via the ubiquitination pathway, or NFKBIB), or RELB to form the NFKB complex, or T, such as STAT, thereby allowing activation of the NF-kappa-B complex, which inactivate NF-kappa-B by trapping it in the cytoplasm, NFKB1 or NFKB2 is bound to REL |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
I kappa B epsilon, IKB epsilon, IKB epsilon S, IKB epsilon Ser157, IKBE, IkB E, IkappaBepsilon, MGC72568, NF kappa B inhibitor epsilon, NF kappa BIE, NFKBIE, NFkappa BIE, NFkappaB inhibitor epsilon, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor epsilon, OTTHUMP00000016522, Slc35b2, member B2, p-IKB epsilon S157, p-IKB epsilon Ser157, solute carrier family 35, NFKBIE phospho S157 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IKB epsilon (Ser157) Conjugated |
| Short name: |
Conjugated, IKB epsilon (Ser157) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, IKB epsilon (Ser157) (Antibody to) |
| Alternative technique: |
antibodies |