| Long name: |
Biotin Conjugated, NFKBIA (Tyr42) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NFKBIA Tyr42 |
| Specificity: |
This is a highly specific antibody against NFKBIA Tyr42 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr42 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human IKB alpha around the phosphorylation site of Tyr42 |
| Gene ID number: |
4792 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Aug 2011], Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease, The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses, The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export, [provided by RefSeq, which contain multiple ankrin repeat domains, This gene encodes a member of the NF-kappa-B inhibitor family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
IKBA MAD-3 IkappaBalpha |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NFKBIA (Tyr42) Conjugated |
| Short name: |
Conjugated, NFKBIA (Tyr42) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
a (Tyr42) (Antibody to), biotinilated coupled, nuclear factor on kappa light polypeptide gene enhancer in B-cells inhibitor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BIKBA and IDBG-632547 and ENSBTAG00000016683 and 282291, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051059 and NF-kappaB binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070417 and cellular response to cold and biological process this GO :0070427 and nucleotide-binding oli this GO merization domain containing 1 signaling pathway and biological process this GO :0070431 and nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process, IKBA and MAD-3 and NFKBI, NF-kappaB binding, NFKBIA and IDBG-4758 and ENSG00000100906 and 4792, Nfkbia and IDBG-140708 and ENSMUSG00000021025 and 18035, alpha, nuclei, this GO :0000060 and protein import into nucleus, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0008139 : nuclear localization sequence binding and also this GO :0019899 : enzyme binding and also this GO :0031072 : heat shock protein binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0032403 : protein complex binding and also this GO :0042802 : identical protein binding and also this GO :0051059 : NF-kappaB binding, this GO :0008134 : transcription factor binding, this GO :0008139 : nuclear localization sequence binding, this GO :0019899 : enzyme binding, this GO :0031072 : heat shock protein binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0032403 : protein complex binding, this GO :0042802 : identical protein binding, this GO :0051059 : NF-kappaB binding, translocation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007253 and cytoplasmic sequestering of NF-kappaB and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008139 and nuclear localization sequence binding and molecular function this GO :0010468 and regulation of gene expression and biological process this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0010888 and negative regulation of lipid storage and biological process this GO :0016032 and viral process and biological process this GO :0019899 and enzyme binding and molecular function this GO :0031072 and heat shock protein binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032270 and positive regulation of cellular protein metabolic process and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033256 and I-kappaB/NF-kappaB complex and cellular component this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042345 and regulation of NF-kappaB import into nucleus and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042994 and cytoplasmic sequestering of transcription factor and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0045087 and innate immune response and biological process this GO :0045638 and negative regulation of myeloid cell differentiation and biological process this GO :0045746 and negative regulation of Notch signaling pathway and biological process this GO :0045893 and positive regulation of transcription, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor |
| Identity: |
7797 |
| Gene: |
NFKBIA |
More about : NFKBIA |
| Long gene name: |
NFKB inhibitor alpha |
| Synonyms gene: |
NFKBI |
| Synonyms gene name: |
alpha , nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor |
| Synonyms name: |
NF-kappa-B inhibitor alpha |
| Locus: |
14q13, 2 |
| Discovery year: |
1992-02-13 |
| Entrez gene record: |
4792 |
| Pubmed identfication: |
1829648 |
| RefSeq identity: |
NM_020529 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000140220 |
| Locus Specific Databases: |
NFKBIAbase: Mutation registry for Autosomal dominant anhidrotic ectodermal dysplasia and T-cell immunodeficiency LRG_89 |