| Long name: |
p38 MAPK (Tyr323) Primary Polyclonal Antibody |
| Also known as: |
p38 MAPK (Tyr323) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
p38 MAPK Tyr323 |
| Specificity: |
This is a highly specific antibody against p38 MAPK Tyr323 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr323 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human MAPK14 around the phosphorylation site of Tyr323 |
| Gene ID number: |
1432 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Cdc25B, Cdc25C and binds to the kinase interaction domain in the protein tyrosine phosphatase PTPRR, Downstream targets of p38 include the transcription factors ELK1 and ATF2 and the kinases MAPKAPK2 and MAPKAPK5, Dual phosphorylation by MAP2K3 and MAP2K6 is required for activation of p38 MAPK, It interacts with MAX, It is activated by environmental stress, gene knock out studies have also revealed a critical role for p38 in cardiac remodeling, many proinflammatory cytokines and lipopolysaccharide, p38 MAPK plays a critical role in the initiation of G2 delay after ultraviolet radiation, p38 MAPK plays a role in the production of IL6 and is thought to stabilize erythropoietin production during hypoxic stress, this interaction retains p38 MAPK in the cytoplasm, within the activation loop, p38 is a 38 kDa Stress Activated Protein Kinase/Map Kinase (SAPK/MAPK) that is fully activated by dual phosphorylation on threonine 180 and tyrosine 182 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CSAID Binding Protein 1, CSAID binding protein, CSAID-binding protein, CSBP, CSBP 1, CSBP 2, CSBP1, CSBP2, CSPB 1, CSPB1, Csaids binding protein, Cytokine suppressive anti inflammatory drug binding protein, Cytokine suppressive anti-inflammatory drug-binding protein, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, MAX-interacting protein 2, MK14_HUMAN, Mitogen Activated Protein Kinase 14, Mitogen activated protein kinase p38 alpha, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38 alpha, Mxi 2, Mxi2, PRKM14, PRKM15, RK, SAPK 2A, SAPK2A, Stress Activated Protein Kinase 2A, p38, p38 ALPHA, p38 MAP kinase, p38 MAPK, p38 mitogen activated protein kinase, p38ALPHA, p38alpha Exip, MAPK14phospho T323 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
p38 MAPK (Tyr323) |
| Short name: |
p38 MAPK (Tyr323) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p38 MAPK (Tyr323) (Antibody to) |
| Alternative technique: |
antibodies |