| Long name: |
ALEXA FLUOR 647 Conjugated, ILK-1(Ser246) Polyclonal Antibody |
| Also known as: |
Anti-ILK-1 Ser246 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ILK-1 Ser246 |
| Specificity: |
This is a highly specific antibody against ILK-1 Ser246 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser246 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ILK-1 around the phosphorylation site of Ser246 |
| Gene ID Number: |
3611 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
3 Negative regulation of ILK is mediated by two phosphatases: PTEN, ILK is constitutively active, In tumor cells that do not express PTEN protein, The kinase activity of ILK is low in non-activated cells, a PP2C protein phosphatase, a tumor suppressor lipid sphatase, anchorage-dependent cell cycle progression, and ILKAP, and growth factor signaling, its activity is stimulated by cell-ECM interactions and by certain growth factors, oncogenic transformation, The ILK protein is important in different biological pathways such as cell adhesion |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
59 kDa serine/threonine protein kinase, 59 kDa serine/threonine-protein kinase, DKFZp686F1765, EC 2, ILK, ILK 1, ILK 2, ILK-1 phospho Ser246, ILK-2, ILK1, ILK2, ILK_HUMAN, Integrin linked Kinase, Integrin linked Kinase 2, Integrin linked protein kinase, Integrin-linked protein kinase, p-ILK-1 Ser246, p59, p59ILK, 1, 7, 11, ILK-1 phospho S246 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ILK-1(Ser246) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ILK-1(Ser246) |
| Short name: |
ILK-1(Ser246) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, integrin-linked kinase-1(Ser246) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050772 and positive regulation of axonogenesis and biological process this GO :0050775 and positive regulation of dendrite morphogenesis and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :2000178 and negative regulation of neural precursor cell proliferation and biological process, HEL-S-28 and ILK-1 and ILK-2 and P59 and p59ILK, ILK and IDBG-29381 and ENSG00000166333 and 3611, ILK and IDBG-634121 and ENSBTAG00000000696 and 540207, Ilk and IDBG-204955 and ENSMUSG00000030890 and 16202, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001725 and stress fiber and cellular component this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007569 and cell aging and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009966 and regulation of signal transduction and biological process this GO :0010667 and negative regulation of cardiac muscle cell apoptotic process and biological process this GO :0010761 and fibroblast migration and biological process this GO :0014044 and Schwann cell development and biological process this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004871 : signal transducer activity and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004871 : signal transducer activity, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0017124 : SH3 domain binding, this GO :0019901 : protein kinase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017124 : SH3 domain binding and also this GO :0019901 : protein kinase binding, transferring phosphorus-containing groups and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0021675 and nerve development and biological process this GO :0022011 and myelination in peripheral nervous system and biological process this GO :0030017 and sarcomere and cellular component this GO :0030027 and lamellipodium and cellular component this GO :0030030 and cell projection organization and biological process this GO :0030054 and cell junction and cellular component this GO :0030335 and positive regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030513 and positive regulation of BMP signaling pathway and biological process this GO :0032288 and myelin assembly and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0034329 and cell junction assembly and biological process this GO :0034446 and substrate adhesion-dependent cell spreading and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043034 and costamere and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043195 and terminal bouton and cellular component this GO :0043198 and dendritic shaft and cellular component this GO :0043206 and extracellular fibril organization and biological process this GO :0043234 and protein complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045197 and establishment or maintenance of epithelial cell apical/basal polarity and biological process this GO :0045663 and positive regulation of myoblast differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045773 and positive regulation of axon extension and biological process this GO :0045893 and positive regulation of transcription, integrin-linked kinase |