| Long name: |
Tau protein(Ser721) Primary Polyclonal Antibody |
| Also known as: |
Tau protein(Ser721) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Tau protein Ser721 |
| Specificity: |
This is a highly specific antibody against Tau protein Ser721 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser721 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser721 [DT(p-S)PR] |
| Gene ID number: |
4137 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome, It expressed in neurons, PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system, Tau proteins subcellular located in the axons of neurons, The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization, and might be involved in the establishment and maintenance of neuronal polarity, in the cytoso l and in association with plasma membrane components, suggesting that tau functions as a linker protein between both, Tau proteins are important Promotes microtubule assembly and stability |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AI413597, AW045860, DDPAC, Disinhibition dementia parkinsonism amyotrophy complex, FLJ31424, FTDP 17, FTDP17, G Protein beta 1 gamma 2 subunit interacting factor 1, G protein beta1/gamma2 subunit interacting factor 1, MAPT, MAPTL, MGC134287, MGC138549, MGC156663, MSTD, MTBT1, MTBT2, Microtuble-associted protein Tau, Microtubule associated protein tau isoform 4, Mtapt, Neurofibrillary tangle protein, PHF tau, PHF-tau, PPND, Paired helical filament tau, RNPTAU, TAU_HUMAN, Tauopathy and respiratory failure, included, pTau, MAPTphospho S721 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Tau protein(Ser721) |
| Short name: |
Tau protein(Ser721) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Taurine protein(Ser721) (Antibody to) |
| Alternative technique: |
antibodies |