| Long name: |
Seladin 1 Primary Polyclonal Antibody |
| Also known as: |
Seladin 1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Seladin 1 |
| Specificity: |
This is a highly specific antibody against Seladin 1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Seladin 1 |
| Gene ID number: |
1718 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In addition, Seladin 1 has an anti-apoptotic function by reducing caspase 3 activity during oxidative stress-induced apoptosis and protecting cells against amyloid-beta peptide-induced apoptosis, Several studies have identified a reduction in expression levels of this enzyme in brain regions affected by Alzheimer's disease (hippocampus and the subventricular zone), adrenal tissues and adrenal tumours, during cholesterol biosynthesis, where this enzyme catalyzes the reduction of the delta-24 double bond of sterol intermediates such as desmosterol, Seladin 1 is highly expressed in brain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
24 dehydrocholesterol reductase, 3-beta-hydroxysterol delta-24-reductase, DCE, DHCR24, Desmosterol to cholesterol enzyme, Diminuto dwarf1 homolog, SELADIN1, Seladin-1, Selective AD indicator 1, Selective Alzheimer's Disease Indicator 1, Seladin1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Seladin 1 |
| Short name: |
Seladin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Seladin 1 (Antibody to) |
| Alternative technique: |
antibodies |