| Long name: |
Cy7 Conjugated, GABBR2 (Ser783) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GABBR2 Ser783 |
| Specificity: |
This is a highly specific antibody against GABBR2 Ser783 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser783 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human GABBR2 around the phosphorylation site of Ser783 |
| Gene ID number: |
9568 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, Plays a critical role in the fine-tuning of inhibitory synaptic transmission, Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis, muscle relaxation and antinociception, slow wave sleep, stimulates phospholipase A2, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials, Receptor for GABA |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
HG20 GABABR2 GPRC3B |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
GABBR2 (Ser783) Conjugated |
| Short name: |
Conjugated, GABBR2 (Ser783) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, GABBR2 (Ser783) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4507 |
| Gene: |
GABBR2 |
More about : GABBR2 |
| Long gene name: |
gamma-aminobutyric acid type B receptor subunit 2 |
| Synonyms gene: |
GPR51 |
| Synonyms gene name: |
2 , G protein-coupled receptor 51 gamma-aminobutyric acid (GABA) B receptor |
| Locus: |
9q22, 33 |
| Discovery year: |
1999-04-23 |
| GenBank acession: |
AF069755 |
| Entrez gene record: |
9568 |
| Pubmed identfication: |
10087195 |
| Classification: |
Gamma-aminobutyric acid type B receptor subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000020345 |