| Long name: |
SLK (Tyr530) Primary Polyclonal Antibody |
| Also known as: |
SLK (Tyr530) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SLK Tyr530 |
| Specificity: |
This is a highly specific antibody against SLK Tyr530 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr530 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human FYN around the phosphorylation site of Tyr530 |
| Gene ID number: |
2534 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Fyn associates with the T-cell antigen receptor and Thy1, Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation, Fyn is expressed predominately in tissues of neuronal and hematopoietic origin, Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation, Fyn is very strongly similar to mouse Fyn, In T cells, Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing, The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR, non-receptor protein tyrosine kinase approximately 59kDa, v-yes and c-src, which belongs to the Src family of cytoplasmic tyrosine kinases, which may act as substrates or regulators of Fyn activity, Fyn is a membrane-associated |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C syn protooncogene, FYN, FYN oncogene related to SRC FGR YESï, MGC45350ï, OKT3 induced calcium influx regulatorï, P59 FYN, Protein tyrosine kinase fyn, Proto oncogene tyrosine protein kinase fyn, Protooncogene Syn, SLK, SYN, Src like kinase, Src yes related novel gene, Src/yes related novel gene, Tyrosine kinase p59fyn T, Tyrosine kinase p59fynT, p-Fyn phospho Y530, ¼, ¼, ¼, &rsaquo, &rsaquo, &rsaquo, Fyn phospho Y530 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SLK (Tyr530) |
| Short name: |
SLK (Tyr530) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
STE20-like kinase (Tyr530) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, SLK and IDBG-639375 and ENSBTAG00000001017 and 535342, SLK and IDBG-88663 and ENSG00000065613 and 9748, Slk and IDBG-174800 and ENSMUSG00000025060 and 20874, bA16H23, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity, transferring phosphorus-containing groups and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0046777 and protein autophosphorylation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, 1 and LOSK and se20-9 and STK2, STE20-like kinase |
| Identity: |
4037 |
| Gene: |
FYN |
More about : FYN |
| Long gene name: |
FYN proto-oncogene, Src family tyrosine kinase |
| Synonyms gene name: |
FGR, FYN oncogene related to SRC, YES |
| Synonyms: |
SYN SLK MGC45350 |
| Locus: |
6q21 |
| Discovery year: |
1988-08-19 |
| GenBank acession: |
AK056699 |
| Entrez gene record: |
2534 |
| Pubmed identfication: |
3526330 |
| Classification: |
SH2 domain containing Src family tyrosine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000016305 |