| Long name: |
DAXX (Ser517) Primary Polyclonal Antibody |
| Also known as: |
DAXX (Ser517) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DAXX Ser517 |
| Specificity: |
This is a highly specific antibody against DAXX Ser517 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser517 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human DAXX around the phosphorylation site of Ser517 |
| Gene ID number: |
1616 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A novel DD containing molecule was recently cloned from mouse, Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED3 protease family, Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N terminal kinase (JNK) pathway, Daxx is a death domain containing important intermediate in the Fas mediated apoptosis, It is widely expressed in fetal and adult human and mouse tissue, TNFR1 and Fas, human and monkey and designated Daxx, indicating its important function in Fas signaling pathways, occurs during normal cellular differentiation and development of multicellular organisms, or programmed cell death, Apoptosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BING2, DAP 6, DAP6, DAXX_HUMAN, Death associated protein 6, Death domain associated protein 6, EAP 1, EAP1, ETS1 associated protein 1, Fas death domain associated protein, MGC126245, MGC126246, hDaxx, BING 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DAXX (Ser517) |
| Short name: |
DAXX (Ser517) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
death-domain associated protein (Ser517) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BING2 and DAP6 and EAP1, DAXX and IDBG-629026 and ENSBTAG00000016830 and 504336, DAXX and IDBG-82726 and ENSG00000204209 and 102723452, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0016032 and viral process and biological process this GO :0016605 and PML body and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030295 and protein kinase activator activity and molecular function this GO :0030521 and androgen receptor signaling pathway and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0031396 and regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0042393 and histone binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0050681 and androgen receptor binding and molecular function this GO :0070603 and SWI/SNF superfamily-type complex and cellular component this GO :0097190 and apoptotic signaling pathway and biological process this GO :1901216 and positive regulation of neuron death and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, Daxx and IDBG-168138 and ENSMUSG00000002307 and 13163, androgen receptor binding, centromeric region and cellular component this GO :0000792 and heterochromatin and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002039 and p53 binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006334 and nucleosome assembly and biological process this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, nuclei, this GO :0000281 and mitotic cytokinesis and biological process this GO :0000775 and chromosome, this GO :0002039 : p53 binding, this GO :0002039 : p53 binding and also this GO :0003714 : transcription corepressor activity and also this GO :0005057 : receptor signaling protein activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0030295 : protein kinase activator activity and also this GO :0031072 : heat shock protein binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0042393 : histone binding and also this GO :0042803 : protein homodimerization activity and also this GO :0047485 : protein N-terminus binding and also this GO :0050681 : androgen receptor binding, this GO :0003714 : transcription corepressor activity, this GO :0005057 : receptor signaling protein activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0030295 : protein kinase activator activity, this GO :0031072 : heat shock protein binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0042393 : histone binding, this GO :0042803 : protein homodimerization activity, this GO :0047485 : protein N-terminus binding, this GO :0050681 : androgen receptor binding, 1616, death-domain associated protein |
| Identity: |
2681 |
| Gene: |
DAXX |
More about : DAXX |
| Long gene name: |
death domain associated protein |
| Synonyms gene name: |
death-associated protein 6 |
| Synonyms: |
DAP6 |
| Locus: |
6p21, 32 |
| Discovery year: |
1998-03-25 |
| GenBank acession: |
AF006041 |
| Entrez gene record: |
1616 |
| Pubmed identfication: |
9407001 9215629 |
| Havana BLAST/BLAT: |
OTTHUMG00000031203 |