| Long name: |
CREB-1(Ser121) Primary Polyclonal Antibody |
| Also known as: |
CREB-1(Ser121) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CREB-1Ser121 |
| Specificity: |
This is a highly specific antibody against CREB-1Ser121 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser121 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CREB-1 around the phosphorylation site of Ser121 [ TD(p-S)QK] |
| Gene ID number: |
1385 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ATF-1, Although each of the ATF/CREB proteins bind CREs in their homodimeric form, CREB-2, It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), TGACCTCA, The best characterized members of this gene family include CREB-1, both within the ATF/CREB family and with members of the AP-1 transcription factor family, in cerain instances they also bind as heterodimers, these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains, which may reprecent a CREB co-activator, ATF-2, ATF-3and ATF-4, The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Active transcription factor CREB, CREB, CREB 1, CREB1, CREB1, CREB1_HUMAN, MGC9284, Transactivator protein, cAMP response element binding protein, cAMP responsive element binding protein 1, p-CREB-1Ser121, pCREB-1Ser121, CREBSer121 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CREB-1(Ser121) |
| Short name: |
CREB-1(Ser121) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CREB-1(Ser121) (Antibody to) |
| Alternative technique: |
antibodies |