| Long name: |
CFL1 (Tyr89) Primary Polyclonal Antibody |
| Also known as: |
CFL1 (Tyr89) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CFL1 Tyr89 |
| Specificity: |
This is a highly specific antibody against CFL1 Tyr89 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr89 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CFL1/CFL2 around the phosphorylation site of Tyr89 |
| Gene ID number: |
1072 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner, Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton, It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus, The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CFL, CFL 1, CFL1, COF1_HUMAN, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, p18, 18 kDa phosphoprotein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CFL1 (Tyr89) |
| Short name: |
CFL1 (Tyr89) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
cofilin 1 (non-muscle) (Tyr89) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CFL and HEL-S-15, CFL1 and IDBG-57818 and ENSG00000172757 and 1072, CFL1 and IDBG-644243 and ENSBTAG00000021455 and 534553, Cfl1 and IDBG-131972 and ENSMUSG00000056201 and 12631, nuclei, protein binding, this GO :0000281 and mitotic cytokinesis and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001842 and neural fold formation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0003779 and actin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006928 and cellular component movement and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007015 and actin filament organization and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0009615 and response to virus and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016363 and nuclear matrix and cellular component this GO :0022604 and regulation of cell morphogenesis and biological process this GO :0030010 and establishment of cell polarity and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030042 and actin filament depolymerization and biological process this GO :0030168 and platelet activation and biological process this GO :0030836 and positive regulation of actin filament depolymerization and biological process this GO :0030864 and cortical actin cytoskeleton and cellular component this GO :0031258 and lamellipodium membrane and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043200 and response to amino acid and biological process this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, cofilin 1 (non-muscle) |
| Identity: |
1874 |
| Gene: |
CFL1 |
More about : CFL1 |
| Long gene name: |
cofilin 1 |
| Synonyms gene: |
CFL |
| Synonyms gene name: |
cofilin 1 (non-muscle) |
| Locus: |
11q13, 1 |
| Discovery year: |
1991-07-16 |
| GenBank acession: |
X95404 |
| Entrez gene record: |
1072 |
| Pubmed identfication: |
8800436 |
| RefSeq identity: |
NM_005507 |
| Havana BLAST/BLAT: |
OTTHUMG00000166602 |