CDKN1A (Thr57) Antibody, Cy3 Conjugated

Catalog number:	bs-5238R-Cy3 Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	CDKN1A (Thr57) Antibody, Cy3 Conjugated
Quantity:	0.1ml
Related search:	process biological kinase protein response regulation cellular binding cdkna antibody thr cycle component negative serinethreonine positive damage

More details Need more?:

Long name:	Cy3 Conjugated, CDKN1A (Thr57) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	cy3 conjugation kit
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	CDKN1A Thr57
Specificity:	This phosphorylation site is homologous to Thr56 in Mouse, This is a highly specific antibody against CDKN1A Thr57
Modification:	Phosphorylation
Modification site:	Thr57
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	30-70/164
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human CDKN1A around the phosphorylation site of Thr57 [TE(p-T)PL]
Gene ID number:	1026
Swiss Prot:	P38936
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	At higher stoichiometric ratios, Binds to and inhibits cyclin-dependent kinase activity, Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1, inhibits the kinase activity of the cyclin D-CDK4 complex, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression, May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	512, 550nm/570, 615nm
Synonyms:	P21 CIP1 WAF1 SDI1 CAP20 p21CIP1 p21Cip1/Waf1
Properties:	1 of the CDKN1A (Thr57) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	CDKN1A (Thr57) Conjugated
Short name:	Conjugated, CDKN1A (Thr57) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy3
Alternative name:	Cip1) (Thr57) (Antibody to), cyanine 3 coupled, cyclin-dependent kinase inhibitor 1A (p21
Alternative technique:	antibodies
Alternative to gene target:	CAP20 and CDKN1 and CIP1 and MDA-6 and P21 and p21CIP1 and SDI1 and WAF1, CDKN1A and IDBG-630156 and ENSBTAG00000008353 and 513497, CDKN1A and IDBG-85033 and ENSG00000124762 and 1026, Cdkn1a and IDBG-159848 and ENSMUSG00000023067 and 12575, Cip1), metal ion binding, nuclei, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007346 and regulation of mitotic cell cycle and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009411 and response to UV and biological process this GO :0009636 and response to toxic substance and biological process this GO :0010033 and response to organic substance and biological process this GO :0010165 and response to X-ray and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0019912 and cyclin-dependent protein kinase activating kinase activity and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0030332 and cyclin binding and molecular function this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031100 and organ regeneration and biological process this GO :0031668 and cellular response to extracellular stimulus and biological process this GO :0032403 and protein complex binding and molecular function this GO :0033158 and regulation of protein import into nucleus, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000307 and cyclin-dependent protein kinase holoenzyme complex and cellular component this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006977 and DNA damage response, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0019912 : cyclin-dependent protein kinase activating kinase activity and also this GO :0030332 : cyclin binding and also this GO :0032403 : protein complex binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0019912 : cyclin-dependent protein kinase activating kinase activity, this GO :0030332 : cyclin binding, this GO :0032403 : protein complex binding, this GO :0046872 : metal ion binding, translocation and biological process this GO :0034605 and cellular response to heat and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0042493 and response to drug and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043068 and positive regulation of programmed cell death and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045087 and innate immune response and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046685 and response to arsenic-containing substance and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051384 and response to glucocorticoid and biological process this GO :0051412 and response to corticosterone and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0055093 and response to hyperoxia and biological process this GO :0060574 and intestinal epithelial cell maturation and biological process this GO :0070557 and PCNA-p21 complex and cellular component this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0071850 and mitotic cell cycle arrest and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process this GO :0090398 and cellular senescence and biological process this GO :0090400 and stress-induced premature senescence and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :2000278 and regulation of DNA biosynthetic process and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, cyclin-dependent kinase inhibitor 1A (p21
Identity:	1784
Gene:	CDKN1A | More about : CDKN1A
Long gene name:	cyclin dependent kinase inhibitor 1A
Synonyms gene:	CDKN1
Synonyms gene name:	Cip1) , cyclin-dependent kinase inhibitor 1A (p21
Locus:	6p21, 2
Discovery year:	1994-05-24
GenBank acession:	U03106
Entrez gene record:	1026
RefSeq identity:	NM_078467
Havana BLAST/BLAT:	OTTHUMG00000014603

• #process
• #biological
• #kinase
• #protein
• #response
• #regulation
• #cellular
• #binding
• #cdkna
• #antibody
• #thr
• #cycle
• #component
• #negative
• #serinethreonine
• #positive
• #damage