ATF2 (Ser322) Antibody, ALEXA FLUOR 647

Catalog number:	bs-5169R-A647 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	ATF2 (Ser322) Antibody, ALEXA FLUOR 647
Quantity:	100ul
Related search:	atf alexa fluor ser antibody antibodies conjugated gene factor neurotrophic terminal

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Long name:	ALEXA FLUOR 647 Conjugated, ATF2 (Ser322) Polyclonal Antibody
Also known as:	Anti-ATF2 Ser322 PAb ALEXA FLUOR 647
Category:	Conjugated Primary Antibodies
Conjugated with:	647, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ATF2 Ser322
Specificity:	This is a highly specific antibody against ATF2 Ser322
Modification:	Phosphorylation
Modification Site:	Ser322
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from mouse ATF2 around the phosphorylation site of Ser322
Gene ID Number:	11909
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families, ATF2 is abundantly expressed in brain, Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, It is a stronger activator as a heterodimer with cJun than as a homodimer, Many of these genes are important in cell growth and differentiation, Several isoforms of ATF2 arise by differential splicing, Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain, This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase, and UV irradiation, and in stress and immune responses, inflammatory cytokines, seemingly in a protein phosphatase-dependent mechanism, ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	650nm/665nm
Synonyms:	ATF1 ATF2 HFB1-GDNF
Properties:	ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ATF2 (Ser322) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 647, Alexa Fluor
Gene target:	ATF2 (Ser322)
Short name:	ATF2 (Ser322) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 647
Alternative name:	ALEXA FLUOR 647, ATF2 (Ser322) (Antibody to)
Alternative technique:	antibodies
Identity:	4232
Gene:	GDNF | More about : GDNF
Long gene name:	glial cell derived neurotrophic factor
Synonyms name:	astrocyte-derived trophic factor glial cell line derived neurotrophic factor glial derived neurotrophic factor
Locus:	5p13, 2
Discovery year:	1995-05-04
Entrez gene record:	2668
Pubmed identfication:	8493557
RefSeq identity:	NM_000514
Classification:	Endogenous ligands
Havana BLAST/BLAT:	OTTHUMG00000090809

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