| Long name: |
AADACL1 Primary Polyclonal Antibody |
| Also known as: |
AADACL1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
AADACL1 |
| Specificity: |
This is a highly specific antibody against AADACL1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AADACL1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AADAC, AADACL1 hydrolyzes the metabolic intermediate 2-acetyl monoalkylglycerol, However, It plays an important role in the metabolic activation of arylamine substrates to ultimate carcinogens, Some of the lipases involved in this process include arylacetamide deacetylase (AADAC) and its related proteins AADACL1 and AADACL2, a single pass type II membrane protein of the endoplasmic reticulum, and its inactivation results in disruption of ether lipid metabolism in cancer cells and impaired cell migration and tumor growth, intestinal mucosal cells, is expressed in hepatocytes, pancreas and adrenal gland, some of the re-esterified TAG products are returned to the cytosolic pool in the liver, which protects vulnerable body tissues from excess lipotoxic non-esterified fatty acids in the plasma, The assembly of very-low-density lipoproteins (VLDLs) in the secretory apparatus of the hepatocyte relies on the mobilization of triacylglycerol (TAG) from the cytosolic pool by lipolysis and re-esterification |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Arylacetamide deacetylase-like 1, Kiaa1363, NCEH, NCEH1_HUMAN, Nceh1, Neutral cholesterol ester hydrolase, Neutral cholesterol ester hydrolase 1, Arylacetamide deacetylase like 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AADACL1 |
| Short name: |
AADACL1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AADACL1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29260 |
| Gene: |
NCEH1 |
More about : NCEH1 |
| Long gene name: |
neutral cholesterol ester hydrolase 1 |
| Synonyms gene: |
AADACL1 |
| Synonyms gene name: |
arylacetamide deacetylase-like 1 |
| Synonyms: |
KIAA1363 NCEH |
| Locus: |
3q26, 31 |
| Discovery year: |
2005-02-25 |
| GenBank acession: |
AB037784 |
| Entrez gene record: |
57552 |
| Pubmed identfication: |
10718198 |
| RefSeq identity: |
NM_020792 |
| Havana BLAST/BLAT: |
OTTHUMG00000156872 |