Unrip Antibody, ALEXA FLUOR 488

Catalog number:	bs-5132R-A488 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Unrip Antibody, ALEXA FLUOR 488
Quantity:	100ul
Related search:	unrip antibody fluor protein gene strap kinase gemin

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Long name:	ALEXA FLUOR 488 Conjugated, Unrip Polyclonal Antibody
Also known as:	Anti-Unrip PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Unrip
Specificity:	This is a highly specific antibody against Unrip
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Unrip
Gene ID Number:	11171
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	It is associated with the complex in the cytoplasm but not in the nucleus and thus is thought to play a role in it's subcellular localisation, It is the first component of the U snRNP assembly machinery that associates with SMN complex in a compartment-specific way and plays a crucial role in the intracellular distribution of SMN1, Stable expression of STRAP results in activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and in down-regulation of the cyclin-dependent kinase inhibitor p21 (Cip1), Unrip interacts directly with Gemin 6 and Gemin 7 in the SMN complex, Upregulation of STRAP might play a role in tumor development as an early event for colorectal cancers, which results in retinoblastoma protein hyperphosphorylation, It is a ubiquitously expressed protein that acts as an inhibitor of TGF-beta signaling and an important regulator of cell proliferation, Unrip is part of the SMN complex that plays a role in snRNP assembly in the cytoplasm and pre mRNA splicing in the nucleus
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Synonyms:	UNRIP pt-wd MAWD
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Unrip Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	Unrip
Short name:	Unrip Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, Unrip (Antibody to)
Alternative technique:	antibodies
Identity:	30796
Gene:	STRAP | More about : STRAP
Long gene name:	serine/threonine kinase receptor associated protein
Synonyms name:	Unr-interacting protein
Locus:	12p12, 3
Discovery year:	2004-04-19
GenBank acession:	AB024327
Entrez gene record:	11171
RefSeq identity:	NM_007178
Classification:	WD repeat domain containing
Havana BLAST/BLAT:	OTTHUMG00000168791

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