Phospho-Stat3 (Y705) Antibody

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Catalog number: bs-50472R
Price: 509 €
Supplier: MBS Polyclonals
Product name: Phospho-Stat3 (Y705) Antibody
Quantity: 100ug
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More details :

Long name: Phospho-Stat3 (Y705) Primary Polyclonal Antibody
Also known as: Phospho-Stat3 (Y705) PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: Phospho-Stat3 (Y705)
Specificity: This is a highly specific antibody against Phospho-Stat3 (Y705)
Modification(s): Phosphorylation
Modification site(s): Tyr705
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Source: Synthetic peptide
Gene ID number: 6774
Swiss Prot: P40763
Tested Applications: WB
Recommended dilutions: 000), WB (1: 2
Cross reactivity: Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: Activated by IL31 through IL31RA, Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes, Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity, FGFR2, FGFR3 and FGFR4, Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, KITLG/SCF, LEP and other growth factors, May mediate cellular responses to activated FGFR1, May play an apoptotic role by transctivating BIRC5 expression under LEP activation (PubMed:18242580), Mediates the effects of LEP on melanocortin production, Once activated, body energy homeostasis and lactation (By similarity), recruits coactivators, such as CCND1 (PubMed:17344214), such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214), Signal transducer and transcription activator that mediates cellular responses to interleukins
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: ADMIO, ADMIO1, Acute-phase response factor, HIES, STAT3, Signal transducer and activator of transcription 3, APRF
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: Phospho-Stat3 (Y705)
Short name: Phospho-Stat3 (Y705) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: phosphorilated-signal transducer and activator on transcription 3 (acute-phase response factor) (Y705) (Antibody to)
Alternative technique: antibodies

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