| Catalog number: | bs-50472R |
|---|---|
| Price: | 509 € |
| Supplier: | MBS Polyclonals |
| Product name: | Phospho-Stat3 (Y705) Antibody |
| Quantity: | 100ug |
| Related search: |
| Long name: | Phospho-Stat3 (Y705) Primary Polyclonal Antibody |
|---|---|
| Also known as: | Phospho-Stat3 (Y705) PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | Phospho-Stat3 (Y705) |
| Specificity: | This is a highly specific antibody against Phospho-Stat3 (Y705) |
| Modification(s): | Phosphorylation |
| Modification site(s): | Tyr705 |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Source: | Synthetic peptide |
| Gene ID number: | 6774 |
| Swiss Prot: | P40763 |
| Tested Applications: | WB |
| Recommended dilutions: | 000), WB (1: 2 |
| Cross reactivity: | Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Activated by IL31 through IL31RA, Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes, Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity, FGFR2, FGFR3 and FGFR4, Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, KITLG/SCF, LEP and other growth factors, May mediate cellular responses to activated FGFR1, May play an apoptotic role by transctivating BIRC5 expression under LEP activation (PubMed:18242580), Mediates the effects of LEP on melanocortin production, Once activated, body energy homeostasis and lactation (By similarity), recruits coactivators, such as CCND1 (PubMed:17344214), such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214), Signal transducer and transcription activator that mediates cellular responses to interleukins |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | ADMIO, ADMIO1, Acute-phase response factor, HIES, STAT3, Signal transducer and activator of transcription 3, APRF |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | Phospho-Stat3 (Y705) |
| Short name: | Phospho-Stat3 (Y705) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | phosphorilated-signal transducer and activator on transcription 3 (acute-phase response factor) (Y705) (Antibody to) |
| Alternative technique: | antibodies |
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