| Long name: |
ADAM12 Primary Polyclonal Antibody |
| Also known as: |
ADAM12 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ADAM12 |
| Specificity: |
This is a highly specific antibody against ADAM12 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAM12/MLTN |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ADAM 12 (Meltrin-a) is produced as 2 differentially spliced isoforms, ADAM proteins possess a signal-domain, ADAMs are expressed in brain, Zn2+ dependent proteases that are involved in cell-cell, a 718 amino acid secreted form (ADAM12S) and a 881 amino acid membrane-bound form (ADAM12L), a cysteine-rich region, a disintegrin domain (Integrin ligand), a metalloprotease domain, a pro-domain, a transmembrane domain and a cytoplasmic tail (1-3), adhesion, an epidermal growth factor-like domain, and catalyze proteolysis, and intracellular signaling (3), and is involved in egg-sperm fusion (4-6), and modulation of the neurogenic function of Notch and Delta (1-3), and muscle, bone, breast, cell-matrix interface related processes including fertilization, epididymis, fusion, glycosylated, heart, liver, lung, muscle fusion, ovary, placenta, secretion of TNF?(tumor necrosis factor ?, testis, ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
A disintegrin and metalloproteinase domain 12, A disintegrin and metalloproteinase domain 12, ADA12_HUMAN, ADAM 12, ADAM metallopeptidase domain 12, ADAM12, Disintegrin and metalloproteinase domain-containing protein 12, MCMP, MCMPMltna, MCMPMltna, MLTN, MLTNA, Meltrin alpha, Meltrin-alpha, OTTHUMP00000046766, MLTN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ADAM12 |
| Short name: |
ADAM12 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ADAM metallopeptidase domain 12 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADAM12 and IDBG-93032 and ENSG00000148848 and 8038, ADAM12-OT1 and CAR10 and MCMP and MCMPMltna and MLTN and MLTNA, Adam12 and IDBG-211287 and ENSMUSG00000054555 and 11489, BT, Extracellular, SH3 domain binding, this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0007155 and cell adhesion and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007520 and myoblast fusion and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0017124 and SH3 domain binding and molecular function, this GO :0004222 : metalloendopeptidase activity, this GO :0004222 : metalloendopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008237 : metallopeptidase activity and also this GO :0008270 : zinc ion binding and also this GO :0017124 : SH3 domain binding, this GO :0005515 : protein binding, this GO :0008237 : metallopeptidase activity, this GO :0008270 : zinc ion binding, this GO :0017124 : SH3 domain binding, 29890 and IDBG-640937 and ENSBTAG00000012444 and 407229, ADAM metallopeptidase domain 12 |
| Identity: |
190 |
| Gene: |
ADAM12 |
More about : ADAM12 |
| Long gene name: |
ADAM metallopeptidase domain 12 |
| Synonyms gene name: |
a disintegrin and metalloproteinase domain 12 (meltrin alpha) |
| Synonyms: |
MCMPMltna MLTN |
| Synonyms name: |
meltrin alpha |
| Locus: |
10q26, 2 |
| Discovery year: |
1998-12-01 |
| GenBank acession: |
AF023476 |
| Entrez gene record: |
8038 |
| Pubmed identfication: |
9417060 18342566 |
| Classification: |
ADAM metallopeptidase domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019243 |