| Long name: |
Biotin Conjugated, GDF9 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GDF9 |
| Specificity: |
This is a highly specific antibody against GDF9 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
321-371/454 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human GDF9 |
| Gene ID number: |
2661 |
| Swiss Prot: |
O60383 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B, It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells, It suppresses FST and FSTL3 production in granulosa-lutein cells, Promotes cell transition from G0/G1 to S and G2/M phases, Promotes primordial follicle development, Stimulates granulosa cell proliferation, and RB1 phosphorylation, through an increase of CCND1 and CCNE1 expression, Required for ovarian folliculogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GDF9 Conjugated |
| Short name: |
Conjugated, GDF9 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, growth differentiation factor 9 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, GDF9 and IDBG-43527 and ENSG00000164404 and 2661, GDF9 and IDBG-645713 and ENSBTAG00000009478 and 282574, Gdf9 and IDBG-171675 and ENSMUSG00000018238 and 14566, growth factor activity, this GO :0001555 and oocyte growth and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007292 and female gamete generation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :2000870 and regulation of progesterone secretion and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0008083 : growth factor activity, this GO :0008083 : growth factor activity, growth differentiation factor 9 |
| Identity: |
4224 |
| Gene: |
GDF9 |
More about : GDF9 |
| Long gene name: |
growth differentiation factor 9 |
| Locus: |
5q31, 1 |
| Discovery year: |
1997-09-12 |
| Entrez gene record: |
2661 |
| Pubmed identfication: |
7760846 |
| RefSeq identity: |
NM_005260 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000059842 |