GSK3 Alpha(Ser21) Antibody, ALEXA FLUOR 594

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Catalog number: bs-4692R-A594
Price: 659 €
Supplier: acr
Product name: GSK3 Alpha(Ser21) Antibody, ALEXA FLUOR 594
Quantity: 0,1 mg
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More details :

Long name: ALEXA FLUOR 594 Conjugated, GSK3 Alpha(Ser21) Polyclonal Antibody
Also known as: Anti-GSK3 Alpha Ser21 PAb ALEXA FLUOR 594
Category: Conjugated Primary Antibodies
Conjugated with: 594, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: GSK3 Alpha Ser21
Specificity: This is a highly specific antibody against GSK3 Alpha Ser21
Modification: Phosphorylation
Modification Site: Ser21
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 1-50/483
Source: KLH conjugated synthetic phosphopeptide derived from human GSK3 Alpha around the phosphorylation site of Ser21
Gene ID Number: 2931
Swiss Prot: P49840
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: APC and AXIN1, CTNNB1/beta-catenin, Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis, Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease, In Wnt signaling, Is necessary for the establishment of neuronal polarity and axon outgrowth, May also mediate the development of insulin resistance by regulating activation of transcription factors, May be involved in the regulation of replication in pancreatic beta-cells, Regulates glycogen metabolism in liver, Requires primed phosphorylation of the majority of its substrates, Through phosphorylation of the anti-apoptotic protein MCL1, Wnt signaling and regulation of transcription factors and microtubules, but not in muscle, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), may control cell apoptosis in response to growth factors deprivation, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin, Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 590nm/617nm
Synonyms: GSK-3 alpha, GSK3A, Serine/threonine-protein kinase GSK3A, Glycogen synthase kinase-3 alpha
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: 594, ALEXA FLUOR®, Alexa Fluor
Conjugated: Alexa conjugate 1
Description: is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The GSK3 Alpha(Ser21) Antibody
Gene target: GSK3 Alpha(Ser21)
Short name: GSK3 Alpha(Ser21) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 594
Alternative name: ALEXA FLUOR 594, GSK3 a(Ser21) (Antibody to)
Alternative technique: antibodies

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