| Long name: |
Alpha B Crystallin Primary Polyclonal Antibody |
| Also known as: |
Alpha B Crystallin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Alpha B Crystallin |
| Specificity: |
This is a highly specific antibody against Alpha B Crystallin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Alpha B Crystallin |
| Gene ID number: |
1410 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alpha and beta families are further divided into acidic and basic groups, Alpha crystallins are composed of two gene products: alpha-A and alpha-B, Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family, Alpha-A and alpha-B gene products are differentially expressed, Elevated expression of alpha-B crystallin occurs in many neurological diseases, Jul 2008], Mammalian lens crystallins are divided into alpha, Post-translational modifications decrease the ability to chaperone, Seven protein regions exist in crystallins: four homologous motifs, Since lens central fiber cells lose their nuclei during development, The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens, These heterogeneous aggregates consist of 30-40 subunits, They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture, [provided by RefSeq, a connecting peptide, a missense mutation cosegregated in a family with a desmin-related myopathy, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs, and N- and C-terminal extensions, and gamma families, and ubiquitous, beta, beta and gamma crystallins are also considered as a superfamily, for acidic and basic, instead they hold them in large soluble aggregates, making them extremely stable proteins, or enzyme, respectively, respectively, the alpha-A and alpha-B subunits have a 3:1 ratio, these crystallins are made and then retained throughout life, Crystallins are separated into two classes: taxon-specific |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AACRYA, Alpha B crystalline, Alpha crystallin B chain, Alpha crystallin B chain, Alpha-crystallin B chain, AlphaB crystalline, AlphaB-crystallin, CRYA2, CRYAB_HUMAN, CTPP 2, CTPP2, Crystallin alpha B, Crystallin alpha polypeptide 2, HSPB5, Heat shock 20 kD like protein, Heat shock protein beta 5, Heat shock protein beta-5, NY REN 27 antigen, Renal carcinoma antigen NY REN 27, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component, CRYAB |
| Description: |
- or alpha protein sometimes glycoprotein present in blood, The Alpha B Crystallin Antibody is a &alpha |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Alpha B Crystallin |
| Short name: |
Alpha B Crystallin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
a B Crystallin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2389 |
| Gene: |
CRYAB |
More about : CRYAB |
| Long gene name: |
crystallin alpha B |
| Synonyms gene: |
CRYA2 |
| Synonyms gene name: |
alpha B , crystallin |
| Synonyms: |
HSPB5 |
| Locus: |
11q23, 1 |
| Discovery year: |
1987-09-11 |
| Entrez gene record: |
1410 |
| Pubmed identfication: |
8431633 |
| Classification: |
Small heat shock proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000166885 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database LRG_407 |