| Long name: |
KAT8 Primary Polyclonal Antibody |
| Also known as: |
KAT8 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
KAT8/MYST1 |
| Specificity: |
This is a highly specific antibody against KAT8/MYST1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
330-380/458 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KAT8 |
| Gene ID number: |
84148 |
| Swiss Prot: |
Q9H7Z6 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac, As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues, Can also acetylate TP53/p53 at 'Lys-120', May influence the function of ATM, That activity is less specific than the one of the MSL complex, Histone acetyltransferase which may be involved in transcriptional activation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Histone acetyltransferase KAT8, KAT8, Lysine acetyltransferase 8, MOZ, MYST-1, MYST1, PP7073, SAS2 and TIP60 protein 1, YBF2/SAS3, ZC2HC8, hMOF, MOF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
KAT8 |
| Short name: |
KAT8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
K(lysine) acetyltransferase 8 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0016407 and acetyltransferase activity and molecular function this GO :0016573 and histone acetylation and biological process this GO :0016747 and transferase activity, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046972 and histone acetyltransferase activity (H4-K16 specific) and molecular function this GO :0071339 and MLL1 complex and cellular component this GO :0072487 and MSL complex and cellular component, KAT8 and IDBG-27798 and ENSG00000103510 and 84148, Kat8 and IDBG-210450 and ENSMUSG00000030801 and 67773, nuclei, this GO :0000123 and histone acetyltransferase complex and cellular component this GO :0000776 and kinetochore and cellular component this GO :0004402 and histone acetyltransferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006325 and chromatin organization and biological process this GO :0006351 and transcription, this GO :0004402 : histone acetyltransferase activity, this GO :0004402 : histone acetyltransferase activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0016407 : acetyltransferase activity and also this GO :0016747 : transferase activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0016407 : acetyltransferase activity, this GO :0016747 : transferase activity, this GO :0019899 : enzyme binding, this GO :0035064 : methylated histone binding, this GO :0043995 : histone acetyltransferase activity (H4-K5 specific), this GO :0043996 : histone acetyltransferase activity (H4-K8 specific), this GO :0046872 : metal ion binding, this GO :0046972 : histone acetyltransferase activity (H4-K16 specific), transferase activity, transferring acyl groups other than amino-acyl groups, transferring acyl groups other than amino-acyl groups and also this GO :0019899 : enzyme binding and also this GO :0035064 : methylated histone binding and also this GO :0043995 : histone acetyltransferase activity (H4-K5 specific) and also this GO :0043996 : histone acetyltransferase activity (H4-K8 specific) and also this GO :0046872 : metal ion binding and also this GO :0046972 : histone acetyltransferase activity (H4-K16 specific), transferring acyl groups other than amino-acyl groups and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0030099 and myeloid cell differentiation and biological process this GO :0031965 and nuclear membrane and cellular component this GO :0035064 and methylated histone binding and molecular function this GO :0043981 and histone H4-K5 acetylation and biological process this GO :0043982 and histone H4-K8 acetylation and biological process this GO :0043984 and histone H4-K16 acetylation and biological process this GO :0043995 and histone acetyltransferase activity (H4-K5 specific) and molecular function this GO :0043996 and histone acetyltransferase activity (H4-K8 specific) and molecular function this GO :0045892 and negative regulation of transcription, 77188 and IDBG-639557 and ENSBTAG00000010511 and 100125883, K(lysine) acetyltransferase 8 |
| Identity: |
17933 |
| Gene: |
KAT8 |
More about : KAT8 |
| Long gene name: |
lysine acetyltransferase 8 |
| Synonyms gene: |
MYST1 |
| Synonyms gene name: |
MYST histone acetyltransferase 1 K(lysine) acetyltransferase 8 |
| Synonyms: |
MOF FLJ14040 hMOF ZC2HC8 |
| Locus: |
16p11, 2 |
| Discovery year: |
2002-08-06 |
| GenBank acession: |
AF217501 |
| Entrez gene record: |
84148 |
| Pubmed identfication: |
10786633 |
| RefSeq identity: |
NM_032188 |
| Classification: |
Lysine acetyltransferases Zinc fingers C2HC-type |
| Havana BLAST/BLAT: |
OTTHUMG00000132410 |