| Long name: |
ALEXA FLUOR 488 Conjugated, BPI Polyclonal Antibody |
| Also known as: |
Anti-BPI PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BPI |
| Specificity: |
This is a highly specific antibody against BPI |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BPI |
| Gene ID Number: |
671 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
2) neutralization of gram-negative bacterial LPS, 3) opsonization of bacteria to enhance phagocytosis by neutrophils, Binding of BPI to live bacteria via LPS causes anti-infective activites: 1) cytotoxicity via sequential damage to bacterial outer and inner lipid membranes, The cytotoxicity action of BPI is limited to gram negative bacteria, reflecting the high affinity of BPI for bacterial LPS, The antimicrobial protein Bactericidal Permeability Increasing protein (BPI) is a 55 kDa protein found in the primary granules of polymorhonuclear leukocytes (PMN) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
BPIFD1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the BPI Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
BPI |
| Short name: |
BPI Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, bactericidal/permeability-increasing protein (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BPI and IDBG-642592 and ENSBTAG00000014046 and 280734, BPI and IDBG-74654 and ENSG00000101425 and 149684, BPIFD1 and rBPI, Bpi and IDBG-211473 and ENSMUSG00000052922 and 329547, Plasma membranes, lipid binding, this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0008289 and lipid binding and molecular function this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032717 and negative regulation of interleukin-8 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0043031 and negative regulation of macrophage activation and biological process this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001530 : lipopolysaccharide binding, this GO :0001530 : lipopolysaccharide binding and also this GO :0008289 : lipid binding, this GO :0008289 : lipid binding, 671, bactericidal/permeability-increasing protein |
| Identity: |
1095 |
| Gene: |
BPI |
More about : BPI |
| Long gene name: |
bactericidal/permeability-increasing protein |
| Synonyms name: |
BPI fold containing family D, member 1 |
| Locus: |
20q11, 23 |
| Discovery year: |
1992-03-13 |
| GenBank acession: |
J04739 |
| Entrez gene record: |
671 |
| Pubmed identfication: |
8432532 |
| RefSeq identity: |
NM_001725 |
| Classification: |
BPI fold containing |
| Havana BLAST/BLAT: |
OTTHUMG00000032441 |