| Long name: |
FITC Conjugated, ELAC2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ELAC2 |
| Specificity: |
This is a highly specific antibody against ELAC2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ELAC2 |
| Gene ID number: |
60528 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A number of allelic variants have been investigated in hereditary prostate cancer, ELAC2 also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), It is thought to be involved in tRNA maturation, Mutations in this gene result in an increased risk of prostate cancer, acting by removing a 3' trailer from precursor tRNA, and reduced expression can suppress transforming growth factor-beta induced growth arrest, ELAC2 is a zinc phosphodiesterase which displays some tRNA 3' processing endonuclease activity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FLJ10530 HPC2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ELAC2 Conjugated |
| Short name: |
FITC Conjugated, ELAC2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, ELAC2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14198 |
| Gene: |
ELAC2 |
More about : ELAC2 |
| Long gene name: |
elaC ribonuclease Z 2 |
| Synonyms gene name: |
coli) , coli) homolog 2 elaC homolog 2 (E, elaC (E |
| Synonyms name: |
tRNase Z (long form) |
| Locus: |
17p12 |
| Discovery year: |
2000-12-14 |
| GenBank acession: |
AF304370 |
| Entrez gene record: |
60528 |
| Pubmed identfication: |
10986046 16636667 21559454 |
| Havana BLAST/BLAT: |
OTTHUMG00000058764 |