| Long name: |
FITC Conjugated, VAPB Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
VAPB |
| Specificity: |
This is a highly specific antibody against VAPB |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human VAPB |
| Gene ID number: |
9217 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in VAPB are a cause of proximal adult autosomal dominant spinal muscular atrophy [MIM:182980], Spinal muscular atrophies are neurodegenerative disorders characterized by degeneration of lower motor neurons, The patients show a benign course, This form is a late adult onset form of the disease (after age 20 years), also called late onset spinal muscular atrophy Finkel type, leading to progressive paralysis muscular atrophy, most of them remaining ambulatory 10 to 40 years after clinical onset, VAPB contains 1 MSP domain and it may play a role in vesicle trafficking |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
VAP-B VAP-C ALS8 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
VAPB Conjugated |
| Short name: |
FITC Conjugated, VAPB Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, VAPB (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12649 |
| Gene: |
VAPB |
More about : VAPB |
| Long gene name: |
VAMP associated protein B and C |
| Synonyms gene name: |
VAMP (vesicle-associated membrane protein)-associated protein B and C |
| Locus: |
20q13, 32 |
| Discovery year: |
1999-03-19 |
| GenBank acession: |
AF086628 |
| Entrez gene record: |
9217 |
| Pubmed identfication: |
9920726 |
| Havana BLAST/BLAT: |
OTTHUMG00000032840 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_656 |