| Catalog number: | bs-4206R-A350 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | sLOX 1 Antibody, ALEXA FLUOR 350 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 350 Conjugated, sLOX 1 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-sLOX 1 PAb ALEXA FLUOR 350 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 350, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | sLOX 1 |
| Specificity: | This is a highly specific antibody against sLOX 1 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 230-273/273 |
| Subcellular location: | Secreted, Extracellular |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human sLOX 1 |
| Gene ID Number: | 4973 |
| Swiss Prot: | P78380 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Also acts as a receptor for advanced glycation end (AGE) products, Also involved in inflammatory process, In addition to binding oxLDL, Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, activated platelets, apoptotic cells and both Gram-negative and Gram-positive bacteria, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, monocyte adhesion and apoptosis, monocytes, pro-oxidative conditions and apoptosis, resulting in pro-inflammatory responses, thereby participating in cell-mediated antigen cross-presentation, Receptor that mediates the recognition |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 343nm/442nm |
| Synonyms: | C-type lectin domain family 8 member A, CLEC8A, LOX-1, LOXIN, Lectin-like oxLDL receptor 1, Lectin-like oxidized LDL receptor 1, Lectin-type oxidized LDL receptor 1, OLR1, Ox-LDL receptor 1, Oxidized low-density lipoprotein receptor 1, SCARE1, SLOX1, hLOX-1, LOX1 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 350, Alexa Fluor |
| Gene target: | sLOX 1 |
| Short name: | sLOX 1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 350 |
| Alternative name: | ALEXA FLUOR 350, sLOX 1 (Antibody to) |
| Alternative technique: | antibodies |
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